Peripheral Neuropathy Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- People aged 19 years or older
- People who have a fracture at the lower end of one wrist (on one side only, with no break in the skin) confirmed by X-ray
- People whose fracture happened within the last 21 days
- People whose fracture is being treated with surgery that uses a metal plate and screws on the palm side of the wrist
- People considered at risk of developing a condition called CRPS, meaning two or more of these apply: pain rated 5 or higher out of 10 within a week of injury and continuing; a depression screening score of 16 or higher at the first visit; or identifying as female
- People who are already showing early signs of CRPS based on a specific set of medical criteria called the Budapest CRPS Criteria
- People who have given their informed consent to take part in the trial
Who may not be able to join:
- People who have previously broken the same wrist
- People who have nerve or blood vessel damage connected to the wrist fracture
- People who have other injuries to their limbs or multiple serious injuries that could affect their recovery or the study results, as judged by the trial investigator
- People who have a known allergy to prednisone (a type of steroid medication) or to any ingredients in the placebo (inactive treatment)
- People for whom prednisone or the placebo ingredients are medically unsuitable for any reason
- People who are already taking a steroid medication (called a glucocorticoid)
- People who currently have an active bacterial, viral, or fungal infection
- People who have been diagnosed with diabetes
- People who are pregnant, planning to become pregnant, or currently breastfeeding
- People who are unlikely to be able to attend all required follow-up visits, as judged by the trial investigator
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: David Stockton, MD, MASc, FRCSC, University of British Columbia
Phone: 604-875-5809
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Proportion of patient recruitment; Proportion of patient adherence to treatment allocation and protocol - determined by patient self-reporting; Proportion of patients with missing data from secondary and tertiary outcomes; Proportion of patient consent withdrawal from the study; Proportion of complete patient follow up at 6 months
Can't join this trial?
Data last synced from ClinicalTrials.gov: 19 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.