Peripheral Neuropathy Trial, Recruiting NCT06465810 Sponsor: AstraZeneca Condition: Peripheral Neuropathy
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Peripheral Neuropathy Trial, Recruiting

NCT06465810
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who are willing and able to give written consent to take part in the study
  • People who have a confirmed diagnosis of amyloid transthyretin (ATTR) amyloidosis (a condition where a specific protein builds up and damages organs)
  • People who are 18 years of age or older at the time of signing the consent form
  • People who are willing and able to complete electronic health questionnaires as part of the study

Who may not be able to join:

  • People who are currently taking part in another clinical trial for ATTR amyloidosis
  • People who were involved in planning or running this study
  • People who have a different type of amyloidosis, specifically primary (AL) amyloidosis or serum protein A (AA) amyloidosis, rather than the ATTR type
  • People who have ATTR amyloidosis but have no symptoms, or who carry the genetic mutation linked to ATTR amyloidosis but have not developed the condition

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 9 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Phone: 1-877-240-9479

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Sponsor
Registry
ClinicalTrials.gov
Start date
25 June 2024
Est. completion
29 December 2031

Where this trial is recruiting

🇨🇦 Canada 🇨🇳 China 🇩🇪 Germany 🇪🇸 Spain 🇬🇧 United Kingdom 🇺🇸 United States

Primary endpoints

Demographic characteristics (overall and in patients initiating a treatment with eplontersen); Treatment patterns (overall and in patients initiating a treatment with eplontersen); Clinical characteristics (overall and in patients initiating a treatment with eplontersen); Findings from biopsy (overall and in patients initiating a treatment with eplontersen); Findings from Cardiovascular magnetic resonance imaging (CMR) (overall and in patients initiating a treatment with eplontersen); Findings from Bone tracer cardiac scintigraphy (overall and in patients initiating a treatment with eplonterse...

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 9 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov