Pancreatic Cancer Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• You are willing and able to sign a consent form agreeing to take part in the study.
• You are between 18 and 75 years old (any gender).
• Your doctors expect you to live for at least 3 more months.
• You are generally well enough to carry out daily activities with little or no limitation (confirm with trial site for exact fitness level required).
• You can provide a preserved tissue sample from a biopsy taken within the last 3 years.
• You have at least one tumor that can be measured on a CT or MRI scan, meeting specific size requirements (confirm with trial site).
• You have advanced pancreatic cancer confirmed by laboratory testing of tissue or cells, and your cancer has worsened after at least two rounds of standard treatment, you could not tolerate standard treatment due to serious side effects, or no standard treatment is available for you.
• You have suitable veins for blood collection, with no medical reasons preventing a blood separation procedure.
• Your blood counts, liver, kidneys, and clotting function are all at acceptable levels as measured by blood tests (confirm with trial site for exact values).
• If you are able to have children (male or female), you agree to use effective contraception during the study and for 6 months after treatment ends; women who could become pregnant must have a negative pregnancy test within 3 days before starting treatment.

Who may not be able to join:

• You have cancer that has spread to the brain or central nervous system and is not yet treated or stable.
• You have HIV, active hepatitis B, active hepatitis C, or active syphilis.
• You have a mental health condition that would make it difficult to cooperate with treatment or assessments.
• You have a serious autoimmune disease and have been taking immune-suppressing medication long-term.
• You have an active or uncontrolled infection requiring treatment within the 14 days before joining the trial.
• You have certain serious ongoing health conditions, such as unstable heart problems, a recent stroke or heart attack (within 6 months), severe heart failure, serious irregular heartbeat, or uncontrolled high blood pressure.
• You have significant problems with the functioning of important organs such as the lungs, brain, or kidneys.
• You have had major surgery or a serious injury within 4 weeks before the cell therapy, or major surgery is planned during the study.
• You have received chemotherapy, immunotherapy, or certain targeted drug treatments within approximately 1–2 weeks before the blood collection procedure (confirm with trial site for exact timing).
• You have received CAR-T or TCR-T cell therapy (specialised immune cell treatments) within the last 6 months.
• You have a history of severe allergies or serious allergic reactions.
• You currently need blood-thinning (anticoagulant) medication.
• You are pregnant, breastfeeding, or planning to become pregnant within six months (applies to both men and women).
• The trial doctors have identified any other reason they feel makes participation unsuitable for you.

Important: Always verify eligibility with the trial site directly before applying.