Phase 2 Pancreatic Cancer Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• People who have been diagnosed with locally advanced, unresectable, or metastatic pancreatic cancer that is not suitable for curative treatment, confirmed by a tissue biopsy.
• People who have received at least one round of chemotherapy (using gemcitabine, 5-fluorouracil/capecitabine, or albumin-bound paclitaxel) and whose cancer has been stable or better for at least 3 months before joining the trial.
• People who have already received targeted therapy (if their cancer has a specific actionable gene mutation) and/or immunotherapy (if their cancer has certain immune-related markers), before joining the trial.
• People whose cancer can be measured using standard imaging criteria.
• People who are in relatively good general health, as assessed by a standard medical scoring system (confirm with trial site).
• People aged 18 years or older.
• Women who could become pregnant must have a negative pregnancy test within 7 days before joining.
• Women who could become pregnant and men must agree to use effective contraception throughout the treatment period and for 90 days after the last dose; men must also not donate sperm during this time.
• People whose blood counts, kidney, liver, and heart function meet specific minimum levels within 14 days before joining (confirm with trial site for exact values).
• People who are willing and able to give written informed consent and follow all study requirements for the full duration of the trial.
• People with no significant heart problems, including no uncontrolled chest pain, severe heart rhythm problems, serious heart lining disease, heart attack in the past year, or advanced heart failure.

Who may not be able to join:

• People who have a known allergy or sensitivity to the drug cetuximab.
• People who have received another experimental treatment within 3 weeks before joining.
• People with a serious non-healing wound, ulcer, bone fracture, recent major surgery, open biopsy, or significant injury within the 28 days before joining.
• People with known active liver disease, HIV, or active Hepatitis B or C infection, or a condition associated with high risk of serious bleeding (note: blood-thinning medication is permitted).
• People with an active infection, or who have taken antibiotics, antifungals, or antivirals within 2 weeks before joining.
• People who have had a heart attack within the past year.
• People with an autoimmune disease that has required ongoing steroid or immune-suppressing medication within the past 2 years (thyroid hormone, insulin, or low-dose replacement steroids are permitted).
• People with any other medical or personal condition that, in the treating doctor's opinion, could affect the trial results or would make participation unsafe or not in the person's best interest.
• Women who are currently breastfeeding.
• People whose treating doctor does not believe they will be able to follow the trial requirements.
• People with a history of active tuberculosis (TB).
• People who have received a live vaccine within 30 days before joining.
• People who are currently imprisoned or incarcerated.
• People who are being held involuntarily for treatment of a psychiatric or physical illness.

Important: Always verify eligibility with the trial site directly before applying.