Early Phase 1 Pancreatic Cancer Trial, Recruiting NCT06496373 Sponsor: Ruijin Hospital Condition: Pancreatic Cancer
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Early Phase 1 Pancreatic Cancer Trial, Recruiting

NCT06496373
Recruiting Early Phase 1

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People aged 18 or older, of any gender, who are willing and able to follow the study procedures as judged by the research team
  • People who have been diagnosed with a cancerous tumour of the pancreas through pathology testing, and who had surgery to remove the tumour between 1 and 3 months ago
  • People whose genetic testing showed no specific abnormalities (called copy number variations or loss of heterozygosity) in genes related to the immune system's ability to recognise cancer cells (confirm with trial site)
  • People whose tumour tissue was analysed using advanced genetic testing, and where that analysis found at least one target (called a neoantigen) that the immune system may be able to recognise, including targets linked to KRAS or TP53 gene mutations
  • People whose overall physical condition means the treating doctor has determined they are not well enough to tolerate chemotherapy, as measured by a standard health scoring system (ECOG score of 2 or higher)

Who may not be able to join:

  • People who have received chemotherapy, certain traditional Chinese medicine treatments with anti-tumour purposes, or other anti-tumour treatments within the 4 weeks before the study drug would first be given
  • People with a history of a lung condition called interstitial lung disease or pulmonary fibrosis (scarring of the lung)
  • People with other serious or uncontrolled health conditions that may affect participation, including a history of severe drug allergies, known allergies to tumour vaccines or related treatment components, severe reactions to similar medications in the past, or a history of immune system deficiency conditions including HIV
  • People whom the research team considers unsuitable for the trial for other reasons

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 12 July 2026
Early Phase 1 studies are small, early exploratory studies that come before the main Phase 1 to 3 testing, so a standard phase success rate does not apply.

Contact this trial

Principal Investigator: Baiyong Shen, M.D&Ph.D, Ruijin Hospital

Phone: 18817821319

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Early Phase 1
Sponsor
Registry
ClinicalTrials.gov
Start date
16 July 2024
Est. completion
30 June 2026

Where this trial is recruiting

🇨🇳 China

Primary endpoints

Drug related toxicity

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 12 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov