Parkinson's Disease Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- People aged 70 years or younger at the time of joining the trial
- People who have been diagnosed with Parkinson's disease according to an established set of clinical diagnostic guidelines (called MDS criteria)
- People whose first Parkinson's motor symptoms began at least 4 years ago
- People who have moderate or severe problems with impulse control — such as compulsive gambling, hypersexuality, compulsive shopping, binge eating, obsessive hobbies, repetitive purposeless behaviours (called punding), or overuse of medication — based on specific scores on a recognised behaviour rating scale (called the Ardouin scale)
- People whose Parkinson's motor symptoms improve by at least 30% when tested with a levodopa medication test, or who have a classic Parkinson's resting tremor
- People who have already tried adjusting their medication to manage their symptoms
- People who score 24 or higher on a standard memory and thinking test (called MoCA), measured while on their usual medication
- People with a depression score below 20 on a standard scale (called BDI-II), measured while on medication; people with scores between 20 and 28 may still be considered, but only with careful review by a psychiatrist and willingness to follow that process
- People who are able to understand what the study involves and what the treatment procedures require
- People who have provided written consent before any study tests or procedures begin
Who may not be able to join:
- People for whom brain surgery would be medically unsafe for any reason
- People with severe ongoing depression (BDI-II score above 28)
- People who have current thoughts of suicide (based on a specific question on the BDI-II scale)
- People with dementia, indicated by a MoCA score below 24 while on their usual medication
- People who have previously had brain surgery, brain tissue removal (ablation), or a device implanted inside the brain for any movement disorder
- People who already have another active implanted medical device that could interfere with a brain stimulation (DBS) system
- People currently participating in another clinical trial that targets or could interfere with impulse control disorders
- People with a history of recurring seizures or a bleeding stroke
- Women who are able to become pregnant and are not using adequate contraception
- People with a serious illness that significantly reduces life expectancy, where brain stimulation surgery would not be appropriate under standard medical care
- Women who are breastfeeding, or who are of childbearing potential and have a positive pregnancy test, or are not using adequate contraception
- People with any condition that would prevent them from taking part in the study or completing study procedures
- People with any significant health condition likely to interfere with study procedures or make it difficult to assess the study's results
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: Ines Deboves, MD, University Hospital Bern, Inselspital, Department of Neurology
Phone: +49 (0)431 500
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Ardouin Scale of Behaviour in Parkinson's Disease (ASBPD)
Can't join this trial?
Data last synced from ClinicalTrials.gov: 8 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.