Phase 2 Mesothelioma Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• You have been diagnosed with one of the following cancers (confirmed by a tissue sample/biopsy): pancreatic cancer, bile duct cancer (cholangiocarcinoma), liver cancer (hepatocellular carcinoma), stomach cancer, bladder cancer, ovarian cancer, a tumor of the adrenal gland or nearby nerve tissue (pheochromocytoma/paraganglioma), small cell lung cancer, a type of neuroendocrine cancer outside the lungs, mesothelioma, or sarcoma.
• You are scheduled or planned to receive treatment for your cancer.
• Your cancer can be detected and measured through testing.
• You are 18 years of age or older.
• You are well enough to carry out some daily activities, with only limited difficulty (confirm with trial site regarding the specific fitness scale used).
• If you are able to become pregnant or father a child, you must agree to use effective birth control (such as condoms, hormonal methods, an IUD, surgical sterilization, or abstinence) from the start of the study until 2 months after each imaging scan, and you must not freeze or donate sperm during that time.
• If you are currently breastfeeding, you must be willing to stop breastfeeding for 2 months after each study imaging scan.
• You are able to understand the study and are willing to sign a consent form agreeing to take part.

Who may not be able to join:

• You have a history of serious allergic reactions to substances chemically similar to the imaging agent used in this study (called [18F]FAPI-74) or to other agents used in the study.
• You have severe claustrophobia (fear of enclosed spaces) that cannot be managed with oral medication, or any other condition that would prevent you from lying still in a scanning machine for up to 45 minutes.
• You weigh more than 350 lbs., or you are unable to fit inside the imaging scanner.
• You are pregnant (confirmed by a blood or urine pregnancy test at the start of the study).
• You have another serious, uncontrolled illness — such as kidney failure, liver failure, or a mental health condition — that could make it difficult to follow the study requirements or could put you at additional risk.
• Your kidney function is significantly reduced, based on a specific blood test result (confirm with trial site for exact values).
• Your liver enzyme levels are significantly elevated, based on a specific blood test result (confirm with trial site for exact values).

Important: Always verify eligibility with the trial site directly before applying.