Parkinson's Disease Trial, Recruiting NCT06505460 Sponsor: China Medical University Hospital Condition: Parkinson's Disease
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Parkinson's Disease Trial, Recruiting

NCT06505460
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who have been diagnosed with Parkinson's disease based on established medical guidelines
  • People aged between 21 and 89 years old
  • For the MRI-guided focused ultrasound (MRgFUS) treatment group: people where at least one of the three main Parkinson's symptoms (slowness of movement, tremor, or muscle stiffness) is rated at a moderate level or above
  • For the MRgFUS group: people whose Parkinson's symptoms have not been adequately controlled by the best available medications, including levodopa and other Parkinson's drugs
  • For the MRgFUS group: people who have been on a stable Parkinson's medication routine for at least 30 days
  • For the deep brain stimulation (DBS) treatment group: people who meet Taiwan's national health insurance requirements, which include having had Parkinson's disease for more than 5 years, showing a meaningful improvement in movement with levodopa, and experiencing motor complications such as medication wearing off, unpredictable on-off periods, levodopa-related involuntary movements, or tremor that cannot be controlled by medication

Who may not be able to join:

  • People with moderate-to-severe heart failure (classified as Functional Class III or higher) or advanced cancer that has spread to other parts of the body
  • People whose Parkinson's disease has reached the most severe stage (stage 5 on the Hoehn and Yahr scale), meaning they are confined to a bed or wheelchair and require full assistance
  • For the DBS group: people with significant dementia or major depression

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 28 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Phone: 8864-22052121

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

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Trial details

Status
Recruiting
Phase
Not Applicable
Sponsor
China Medical University Hospital
Registry
ClinicalTrials.gov
Start date
30 April 2024
Est. completion
31 July 2025

Where this trial is recruiting

🇹🇼 Taiwan

Primary endpoints

Electroencephalogram recording before and after the tDCS session; Electromyography recording before and after the tDCS session; Functional magnetic resonance images examination before and after the tDCS session; Change in Unified Parkinson's Disease Rating Scale (UPDRS) Part III before and after the tDCS session UPDRS contains four parts, the third part of which is reported in this outcome.

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov