Parkinson's Disease Trial, Recruiting NCT06506058 Sponsor: University of Minnesota Condition: Parkinson's Disease
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Parkinson's Disease Trial, Recruiting

NCT06506058
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You have been diagnosed with Parkinson's disease (with or without episodes of "freezing" while walking), OR you are a healthy older adult aged 40–80, OR you are a healthy younger adult aged 21–44.
  • You are between 40 and 80 years old (for Parkinson's disease and healthy older adult groups) or between 21 and 44 years old (for the healthy young adult group).
  • You are able to walk at least 50 meters on your own without using a cane, walker, or other walking aid.
  • Healthy older adults must be able to carry out complex daily activities independently, based on reports from a doctor or someone who knows them well.

Who may not be able to join:

  • You have a bone, joint, or muscle problem that affects your ability to stand or walk.
  • You have a history of conditions that significantly affect movement in your legs or lower body.
  • You have vision problems that have not been corrected and that could affect your ability to take part.
  • You have a history of vision or inner-ear (balance) problems that could affect your participation.
  • You have been diagnosed with Lewy body dementia, Multiple System Atrophy, Alzheimer's disease, any form of dementia, or another brain-degenerative condition other than Parkinson's disease.
  • You have a history of seizures, epilepsy, stroke, multiple sclerosis, traumatic brain injury, or other significant neurological conditions.
  • You have a history of muscle or structural problems in your neck or back, including whiplash.
  • You have had surgery on your blood vessels, brain, or heart.
  • You have unexplained recurring headaches or have had a concussion in the last six months.
  • You have moderate to severe hearing loss.
  • You are currently pregnant.
  • You are assessed as not having sufficient ability to give informed consent to participate (confirm with trial site).
  • For certain experiments involving a specific type of electrical stimulation (EVS): you have a history of motion sickness, migraines, or have metal or magnetic devices inside your head, a pacemaker or other implanted device, a deep brain stimulator, or take medications that can cause dizziness.
  • For certain experiments (EVS): you have done intense exercise or consumed alcohol in the 24 hours before testing.
  • For healthy control participants only: you show any signs of Parkinson's-like symptoms or any degree of cognitive impairment, including mild cognitive impairment or dementia.
  • For healthy control participants only: you have an active nervous system, whole-body, or psychiatric condition, or take medications that could affect your thinking, movement, mood, or automatic body functions.

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 5 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Sommer Huffmaster, PhD, University of Minnesota

Phone: 612-505-8325

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Registry
ClinicalTrials.gov
Start date
24 March 2025
Est. completion
1 December 2028

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

timing of trunk muscle torque production; amplitude of trunk muscle torque production; ground reaction force; center of pressure measures of turning and stepping; body segmental angular velocity; motion onset; total distance excursion; Movement amplitude; speed during the slow and fast epochs; duration of freezing events; EVS coherence

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 5 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov