Depression and Anxiety Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• Adults aged 18 to 64 years old (male or female)
• People who are medically stable
• People whose primary diagnosis is Generalised Anxiety Disorder (GAD)
• People who score 15 or higher on a standard anxiety rating scale called the HAM-A
• People who have either been off psychiatric medications for at least 2 weeks before the study starts, or have been on a stable dose of their current medication for at least 6 weeks and are willing to keep that dose unchanged
• People who are able to lie flat on their front or back for up to one hour at a time, as the study involves massage treatment
• People who have a permanent home address
• People who are able to follow the research study schedule and requirements
• People who are able to understand and sign an approved consent form in line with federal and institutional guidelines

Who may not be able to join:

• People who have used nicotine or illicit drugs within the past 3 months, or who take regular or long-term medications that the study doctor believes could affect the results
• People who are pregnant (based on self-report; no pregnancy testing is done as part of the study)
• People who are normally asleep during the day, such as those working night shifts, or who have other habits that regularly disrupt their normal daily sleep-wake cycle
• People who have been on a strict diet of fewer than 1,200 calories per day for 2 or more days in a row within the past month
• People who have drunk heavily on a regular basis in the month before screening, defined as having 5 or more drinks within 2 hours, or 7 or more drinks within 24 hours, happening twice a month or more
• People who started psychotherapy or complementary and alternative medicine (CAM) treatments for psychological distress within the 90 days before screening
• People who have ever been diagnosed with PTSD, bipolar disorder, OCD, or a psychotic disorder, or who currently have an alcohol or substance use disorder
• People who currently have thoughts of harming themselves or others
• People who get massages regularly, defined as averaging 4 or more massages per year over the past 5 years
• People who are currently using any other hands-on or holistic complementary therapies to treat a health concern
• People with a history of head injury or neurological condition that, in the study doctor's opinion, could affect the results or make participation unsafe
• People who have a history of cancer that required chemotherapy or radiation treatment
• People who are unable to have an MRI scan — this includes people with a cardiac pacemaker, hearing implant, any metal in their body or eyes (such as pins, screws, shrapnel, plates, braces, or dentures), or tattoos on the head including permanent makeup, as these may interfere with getting clear images
• People with medical, psychiatric, or cognitive conditions that may affect their ability to understand the study, give consent, or complete the study requirements
• People who are currently taking part in another research study (with the exception of large observational studies such as 'All of Us')

Important: Always verify eligibility with the trial site directly before applying.