Myeloma Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• You understand the study and are willing to sign a consent form, attend follow-up visits, and complete all required steps
• You are between 18 and 75 years old (any gender)
• You have been officially diagnosed with Multiple Myeloma (MM) according to international standards
• Your myeloma can be detected through specific blood or urine tests showing certain protein levels (confirm with trial site for exact measurements)
• You have already been treated with three or more lines of therapy, including at least one of each of three specific types of drugs: a proteasome inhibitor, an immunomodulatory drug, and an anti-CD38 antibody
• Your myeloma has come back or stopped responding to treatment
• Your last treatment did not work, or your disease got worse within 60 days of finishing it
• You have recovered from most side effects of your previous treatments
• You are reasonably active in daily life and are expected to live at least 3 more months (confirm with trial site)
• Your liver, kidneys, heart, and lungs are functioning well enough to meet specific test results (confirm with trial site for exact values)
• A suitable vein can be accessed for a blood collection procedure

Who may not be able to join:

• You have been diagnosed with or treated for another type of cancer (other than multiple myeloma)
• You received certain types of cancer treatments within the past 14 days or within a recent short timeframe before blood is collected for this treatment
• There is any sign or confirmed evidence that myeloma has spread to your brain or spinal fluid, or you have another active brain condition
• You have been diagnosed with certain related blood or protein disorders, such as Waldenström's macroglobulinemia, POEMS syndrome, or AL amyloidosis
• You have tested positive for hepatitis B, hepatitis C, HIV, or have detectable levels of certain viruses (such as CMV or EBV) in your blood
• You have a history of severe allergic reactions
• You have an unstable heart condition, have had a stroke or mini-stroke, or a heart attack within the past 6 months, or have significant heart failure
• You have serious liver, kidney, or metabolic disease that requires ongoing medication
• You have had graft-versus-host disease (a complication from a previous transplant) recently or are taking medication to suppress your immune system for this within the past 6 months
• You have an active autoimmune or inflammatory disease affecting your nervous system
• You have a cancer-related emergency that needs immediate treatment
• You have an infection that is not under control and requires antibiotic treatment
• You received certain medicines to stimulate blood cell growth within 1–2 weeks before the blood collection procedure
• You used steroids or immune-suppressing medicines within 2 weeks before the blood collection procedure
• You had major surgery within 4 weeks before the start of the treatment phase, have not fully recovered, or plan to have major surgery during the study
• You received a live vaccine within 4 weeks before the screening visit
• You have a serious mental illness
• You have a history of heavy alcohol use or drug abuse
• You are pregnant or breastfeeding, or you or your partner plan to have a baby within two years after receiving this treatment
• The trial doctor feels for any other reason that taking part would not be right for you

Important: Always verify eligibility with the trial site directly before applying.