Depression and Anxiety Trial, Recruiting (NCT06542094)

Depression and Anxiety Trial, Recruiting NCT06542094 Sponsor: West China Hospital Condition: Depression and Anxiety

Printed from Voxsanity (voxsanity.com.au) — NCT06542094 — Data sourced from ClinicalTrials.gov. Verify directly with the trial site before attending. Not medical advice.

Back to Depression And Anxiety

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

You are willing to sign a consent form before any study-related activities begin
You are between the ages of 16 and 30, regardless of gender
You have been diagnosed with Major Depressive Disorder (MDD) based on standard medical guidelines (DSM-5)
Your current depressive episode has lasted 2 years or more, OR you have had at least 4 separate depressive episodes with the most recent one lasting at least 1 year
You have tried at least 3 adequate courses of antidepressant medication from 2 or more different types, and they have not worked; and you have either refused, been unable to tolerate, or not responded to electroconvulsive therapy (ECT — a treatment using electrical stimulation)
Your depression is rated as moderate to severe based on standard depression scoring scales (HAMD-17 score of 20 or above, or MADRS score of 25 or above)
You are able to communicate effectively, and you (and your legal guardian, if applicable) are able to sign a written consent form

Who may not be able to join:

You have been diagnosed with bipolar disorder, schizoaffective disorder, schizophrenia, or another psychotic disorder
You have a severe personality disorder
You have a serious physical illness or a brain disease caused by a physical condition
You have been diagnosed with alcohol or drug abuse or dependence within the past year
You have medical conditions that make surgery unsafe, or you are unable to stop taking blood-thinning medications
A brain MRI scan done within the past year showed abnormal findings
You are unable to have an MRI scan for any reason (not related to a DBS device) (confirm with trial site)
You are currently pregnant or breastfeeding
You are already taking part in another unrelated clinical study
Any other factor — such as your home situation, health, mental wellbeing, or where you live — that could put you at risk or prevent you from completing the study (confirm with trial site)

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.

Last synced 16 July 2026

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Phone: +86 13808170699

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Voxsanity

Clinical trials and treatments, explained plainly · voxsanity.com.au

Date:

To: My Doctor

Re: Clinical trial enquiry

I am writing to enquire about the following clinical trial which may be relevant to my care:

Trial: NCT06542094

Sponsor: West China Hospital

Phase: Not Applicable

Status: Recruiting

Condition: Depression and Anxiety

Trial contact: +86 13808170699

More information: https://clinicaltrials.gov/study/NCT06542094

Eligibility summary (AI generated)

Written by an AI model from the ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

You are willing to sign a consent form before any study-related activities begin
You are between the ages of 16 and 30, regardless of gender
You have been diagnosed with Major Depressive Disorder (MDD) based on standard medical guidelines (DSM-5)
Your current depressive episode has lasted 2 years or more, OR you have had at least 4 separate depressive episodes with the most recent one lasting at least 1 year
You have tried at least 3 adequate courses of antidepressant medication from 2 or more different types, and they have not worked; and you have either refused, been unable to tolerate, or not responded to electroconvulsive therapy (ECT — a treatment using electrical stimulation)
Your depression is rated as moderate to severe based on standard depression scoring scales (HAMD-17 score of 20 or above, or MADRS score of 25 or above)
You are able to communicate effectively, and you (and your legal guardian, if applicable) are able to sign a written consent form

Who may not be able to join:

You have been diagnosed with bipolar disorder, schizoaffective disorder, schizophrenia, or another psychotic disorder
You have a severe personality disorder
You have a serious physical illness or a brain disease caused by a physical condition
You have been diagnosed with alcohol or drug abuse or dependence within the past year
You have medical conditions that make surgery unsafe, or you are unable to stop taking blood-thinning medications
A brain MRI scan done within the past year showed abnormal findings
You are unable to have an MRI scan for any reason (not related to a DBS device) (confirm with trial site)
You are currently pregnant or breastfeeding
You are already taking part in another unrelated clinical study
Any other factor — such as your home situation, health, mental wellbeing, or where you live — that could put you at risk or prevent you from completing the study (confirm with trial site)

Important: Always verify eligibility with the trial site directly before applying.

Access in Australia: A treatment being studied in a clinical trial is generally not yet listed on the PBS. Where a medicine is not approved or not available through a trial, the TGA Special Access Scheme may allow a doctor to access unapproved therapeutic goods for individual patients. See voxsanity.com.au/sas-navigator/ for a plain English explainer.

This information was sourced from ClinicalTrials.gov via Voxsanity (data last synced 16 July 2026). It is not medical advice. Please verify the trial's current status directly with the trial site before acting.

Trial details

Status

Recruiting

Phase

Not Applicable

Sponsor

West China Hospital

Registry

ClinicalTrials.gov

Start date

3 August 2024

Est. completion

3 July 2026

Where this trial is recruiting

🇨🇳 China

Primary endpoints

Identifying an electrophysiological biomarker of MDD

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 16 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov