Atrial Fibrillation Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- People aged between 18 and 80 years
- People with symptomatic, persistent atrial fibrillation (an irregular heartbeat lasting more than 7 days without returning to normal on its own) that has been present for at least 6 months, with at least two episodes in the past 6 months even after treatment to restore normal rhythm
- People whose atrial fibrillation has not responded well to, or who have had problems tolerating, at least one type of heart rhythm medication
- People diagnosed with heart failure where an ultrasound of the heart shows the heart is pumping at 40% or less of its normal capacity
- People who are willing to receive either medication or surgical treatment as part of the trial
- People who are willing to follow all study requirements throughout the trial and during follow-up, and to sign a consent form
- People who are physically able to complete a 6-minute walking test
- Women who could become pregnant must have a negative pregnancy test result before joining
Who may not be able to join:
- People who have a blood clot in the upper left chamber of the heart
- People whose left upper heart chamber is enlarged beyond a certain size, as measured by ultrasound, MRI, or CT scan
- People with significant inborn heart abnormalities or other medical conditions that the research team considers unsuitable for participation
- People whose atrial fibrillation is caused by a treatable or temporary condition, such as thyroid disease, pericarditis (inflammation around the heart), recent surgery, injury, or alcohol-related causes
- People with heart valve disease that requires surgery
- People with blocked heart arteries that require surgery or a procedure to treat them
- People who have previously had a procedure to deliberately block the heart's electrical relay node (atrioventricular node ablation)
- People with liver failure
- People with kidney failure who require dialysis
- People who are unable to take blood-thinning medications (anticoagulation therapy)
- People who are currently taking part in another clinical trial of an experimental drug or device
- People with severe lung disease
- People who have previously had a catheter-based procedure to treat atrial fibrillation inside the left upper chamber of the heart
- People who have had a blood clot-related event, such as a stroke, within the past 90 days
- People who are pregnant
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Phone: 3973183686
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Freedom from Atrial Fibrillation/Atrial Flutter (AT/AF) Recurrence; Change in NT-proBNP Levels; Change in Left Ventricular Ejection Fraction (LVEF); Change in 6-Minute Walk Test Distance; Change in NYHA Functional Class
Can't join this trial?
Data last synced from ClinicalTrials.gov: 26 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.