Phase 3 Depression and Anxiety Trial, Recruiting NCT06590025 Sponsor: Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau Condition: Depression and Anxiety
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Phase 3 Depression and Anxiety Trial, Recruiting

NCT06590025
Recruiting Phase 3

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • Adults aged 18 or older who have been diagnosed with major depression (either currently or in a recent episode that has improved), with depression symptoms up to a moderate level based on a standard rating scale
  • People whose depression is accompanied by noticeable thinking or memory difficulties, as measured by a specific cognitive test
  • People who are also experiencing difficulties with day-to-day functioning, such as work, social activities, or self-care, as measured by a standard functional assessment scale

Who may not be able to join:

  • People with an IQ below 85
  • People with an unstable or poorly managed physical health condition that could affect thinking or memory test results
  • People who have taken any of the following medications in the last 4 weeks: steroid medicines (glucocorticoids), probiotics, anti-inflammatory painkillers (such as ibuprofen), certain cholesterol medicines (bile acid sequestrants), immune-suppressing drugs, antihistamines, mast cell stabilisers, or antioxidant supplements
  • People who have taken antibiotic medicines (taken by mouth or injection, affecting the whole body) in the last 2 months
  • People who have had another diagnosed mental health condition (other than a personality disorder or nicotine use) in the last 3 months
  • People with bipolar disorder who have experienced a manic or mixed mood episode in the last 3 months
  • People whose depression meets the criteria for severe treatment-resistant depression (confirm with trial site)
  • People who have received electroconvulsive therapy (ECT) within the past year
  • People who have been receiving another structured psychological therapy programme in the 3 months before the study
  • People who do not have access to a computer or tablet and a reliable internet connection

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 6 July 2026
Phase 3: approximately ~65% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: Maria J Portella, Dr, Institut de Recerca Sant Pau

Phone: +34935537791

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 3
Sponsor
Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Registry
ClinicalTrials.gov
Start date
13 September 2023
Est. completion
1 July 2025

Where this trial is recruiting

🇪🇸 Spain

Primary endpoints

Functioning Assessment Short Test (FAST)

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 6 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov