Pancreatic Cancer Trial, Recruiting

Written by an AI model from the ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• People who fully understand the study and are willing to sign a consent form agreeing to take part
• People aged 18 to 80 years old
• People who have been diagnosed with pancreatic neuroendocrine tumours (any grade) through a tissue or cell sample, and whose condition has continued to worsen after previous treatments such as somatostatin analogues, targeted therapy, or chemotherapy
• People who have at least one tumour that can be measured using standard imaging methods
• People whose last systemic (whole-body) cancer treatment ended at least 7 days ago, or whose localised radiotherapy was completed more than 4 weeks ago
• People whose doctors estimate they are likely to survive for at least 12 weeks
• People whom the study doctor believes may benefit from the treatment
• People who have adequate organ function and bone marrow function (confirm with trial site for specific values)
• People of childbearing potential who agree to use effective contraception during the study and for 6 months after the last dose of study medication

Who may not be able to join:

• People who have been diagnosed with another cancer in the past 5 years, unless it was certain treated skin cancers, successfully removed cervical carcinoma in situ, or treated breast cancer
• People who are currently taking part in another clinical trial or receiving other anti-cancer treatments at the same time
• People who have medical conditions that make the trial drug unsafe for them, such as active bleeding, uncontrolled high blood pressure, severe heart failure, recent major surgery within the last 30 days, or severe liver or kidney problems
• People who have difficulty absorbing medication or who are unable to swallow oral medication
• People who are known to be allergic to any ingredient in the trial drug
• People who are pregnant or breastfeeding
• People who have a large build-up of fluid in the chest or abdomen that requires drainage
• People with significant abnormalities in their health, physical examination, or laboratory test results that the study doctor believes make participation unsafe or could affect the study results
• People who have taken St John's Wort within 3 weeks before starting the trial, or who have taken certain other medications that strongly affect how the body processes drugs (CYP3A4 inducers or inhibitors) within the past 2 weeks (confirm specific medications with trial site)
• People with other serious health or personal circumstances that the study doctor believes make participation unsuitable or unsafe, such as severe diabetes, thyroid disease, certain neurological conditions, or significant mental illness

Important: Always verify eligibility with the trial site directly before applying.