Phase 1 Myeloma Trial, Recruiting

Written by an AI model from the ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• You have been diagnosed with multiple myeloma, confirmed through a tissue test (biopsy).
• Your kidneys are not working at full capacity — specifically, your kidney filtering rate (eGFR) is below 45.
• You are 18 years of age or older.
• You are generally able to carry out normal daily activities with little to no limitation (confirm with trial site).
• You qualify for a specific cancer cell therapy called cilta-cel based on standard medical guidelines.
• Your white blood cell (neutrophil) count meets a minimum level; if it is low due to recent treatment, you may be re-tested during the screening period to check again.
• If you have previously had a stem cell transplant using your own cells, the transplant must have contained a sufficient number of stem cells (confirm with trial site for specific numbers).
• You must have enough of your own stored stem cells available, in case they are needed during treatment.
• If you are a woman who could become pregnant, or a man, you must agree to use reliable birth control throughout the study; you must tell your doctor immediately if pregnancy is suspected.
• You are willing and able to read and sign a consent form agreeing to take part; a legal representative may do this on your behalf if needed.

Who may not be able to join:

• You have another cancer (past or current) that could affect the safety of the treatment or make results harder to measure (confirm with trial site).
• You are currently taking part in another clinical trial involving an experimental treatment.
• You have an uncontrolled serious illness, such as an active infection, severe heart failure, unstable chest pain, or an unstable irregular heartbeat; heart function must meet a minimum standard to be eligible (confirm with trial site).
• You are currently pregnant or breastfeeding; women who could become pregnant must have a negative pregnancy test within 14 days of joining.
• You are HIV-positive and have not had an undetectable viral load for at least 6 months on effective HIV treatment.
• You have chronic hepatitis B virus (HBV) and your viral load is still detectable, even on suppressive treatment.
• You have a history of hepatitis C virus (HCV) that has not been cured, or your viral load is still detectable.

Important: Always verify eligibility with the trial site directly before applying.