Atrial Fibrillation Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- People between 18 and 80 years of age
- People who have been diagnosed with symptomatic paroxysmal atrial fibrillation (an irregular heartbeat that comes and goes) with a history of less than 5 years
- People who have moderate to severe mitral regurgitation (a leaky heart valve) with normal heart pumping function and normal heart wall movement, meeting specific heart measurement thresholds (confirm with trial site)
- People who are willing and able to understand the trial's purpose, sign a consent form (either personally or through a legal representative), and attend all required follow-up visits
Who may not be able to join:
- People whose atrial fibrillation is caused by an electrolyte imbalance, thyroid condition, or another reversible (treatable) cause
- People with active infection of the heart valves (endocarditis) or active rheumatic heart disease, or whose leaky mitral valve is a result of either of these conditions
- People who have moderate to severe narrowing of the mitral valve (mitral stenosis)
- People whose imaging scans show a blood clot in the left side of the heart or in the left atrial appendage (a small pouch in the heart)
- People whose heart pumping strength is below 50%
- People whose left atrial chamber measures more than 50mm
- People who have previously had certain heart procedures, including closure of the left atrial appendage, closure of a hole between the upper heart chambers, or certain valve repairs (applies to some participants — confirm with trial site)
- People who have an implanted heart device such as a defibrillator, pacemaker, or cardiac resynchronisation therapy device
- People who have previously had a metal artificial heart valve or a valve repair device implanted (applies to some participants — confirm with trial site)
- People who have abnormalities such as blood clots, tumours, or other issues near the blood vessels that would interfere with the procedure (applies to some participants — confirm with trial site)
- People who cannot take blood-thinning medications, or who have a history of abnormal blood clotting or bleeding
- People who have an active infection anywhere in the body
- People who are pregnant, breastfeeding, or unable to use contraception during the study period
- People whose life expectancy is less than 12 months
- People who have other conditions or abnormalities that the trial investigators consider would make participation unsuitable (confirm with trial site)
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: Jianan Wang, Dorctor, Second Affiliated Hospital of Zhejiang University, School of Medicine
Phone: 086-571-87784705
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Improvement in MR
Can't join this trial?
Data last synced from ClinicalTrials.gov: 27 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.