Depression and Anxiety Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- People who have been diagnosed with vision impairment caused by an inherited retinal disease (IRD).
- People who have had a clinical examination with an IRD specialist within the three months before being assigned to a study group.
- People who have had a specific type of visual field test (called a Goldmann visual field test, using the III-4e isopter setting) within the past year.
- People who report at least some difficulty in one or more areas measured by the Michigan Retinal Dystrophy Questionnaire (MRDQ), a survey about how the eye condition affects daily life.
- People whose IRD specialist has indicated that their eye condition is not expected to get worse over the next year.
- People who are able to attend 10 weeks of eye rehabilitation therapy sessions and who will be physically located in Michigan during the first 10 months of the study.
Who may not be able to join:
- People who have other eye conditions in addition to their inherited retinal disease, including complications sometimes linked to IRD such as cystoid macular edema (fluid-related swelling in the eye) that requires management (confirm with trial site).
- People whose day-to-day living needs related to their vision loss have already been fully addressed by a low vision specialist connected to the study.
- People who are currently receiving mental health therapy.
- People who show an elevated level of suicidal thoughts or suicide risk, based on a standard screening questionnaire (PHQ-9) and additional information collected at screening.
- People who are taking medication for mental health or psychiatric reasons and have not been on a stable dose of that medication for at least one month.
- People who are unable to complete the tasks required by the study.
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: K. Thiran Jayasundera, MD, MS, University of Michigan
Phone: 734-763-5590
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Determine if LVR improves vision-related disabilities and distress measures by the Michigan Vision-related Anxiety Questionnaire (MVAQ); Determine if LVR improves vision-related disabilities and distress measures by the Michigan Retinal Degeneration Questionnaire (MRDQ); Determine if LVR measures are different between low-distress and high-distress groups accessed at month-6 by MVAQ; Determine if LVR measures are different between low-distress and high-distress groups accessed at month-6 by MRDQ; Determine if adjunctive ERT treatment in the high-distress arms improves vision-related disabiliti...
Can't join this trial?
Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.