Phase 1 Peripheral Neuropathy Trial, Recruiting NCT06667141 Sponsor: Acrivon Therapeutics Condition: Peripheral Neuropathy
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Phase 1 Peripheral Neuropathy Trial, Recruiting

NCT06667141
Recruiting Phase 1

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who have signed a written consent form agreeing to take part in the trial.
  • People who have been confirmed through a tissue or cell sample to have a specific type of solid tumour cancer that has spread to other parts of the body, has come back, or is advanced in the local area.
  • People who are willing to provide a redacted (personally identifying information removed) copy of their pathology report.
  • People who have received no more than 3 rounds of systemic (whole-body) treatment for their recurring cancer.
  • People who are in generally good physical condition (able to carry out normal daily activities with at most minor limitations) and have a life expectancy of at least 3 months.
  • People whose cancer can be measured using standard imaging guidelines, with at least one measurable area of disease visible on scans.
  • People whose liver, kidneys, and other organs are functioning well enough to safely participate.
  • People whose cancer has continued to grow or spread after a previous treatment.

Who may not be able to join:

  • People who have brain metastases (cancer that has spread to the brain) that are causing symptoms.
  • People who have received systemic (whole-body) cancer treatment within the 3 weeks before starting the trial drug.
  • People who have had radiation therapy aimed at curing their cancer within the 4 weeks before starting the trial drug.
  • People who have had radiation therapy for pain or symptom relief within the 2 weeks before starting the trial drug.
  • People who are pregnant or currently breastfeeding.

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 21 July 2026
Phase 1: approximately ~10% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Phone: 617-207-8979

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 1
Sponsor
Acrivon Therapeutics
Registry
ClinicalTrials.gov
Start date
8 October 2024
Est. completion
12 August 2026

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Dose Escalation; Dose Expansion; Dose Expansion; Dose Expansion

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 21 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov