Phase 3 Peripheral Neuropathy Trial, Recruiting (NCT06672237)

Phase 3 Peripheral Neuropathy Trial, Recruiting NCT06672237 Sponsor: Intellia Therapeutics Condition: Peripheral Neuropathy

Printed from Voxsanity (voxsanity.com.au) — NCT06672237 — Data sourced from ClinicalTrials.gov. Verify directly with the trial site before attending. Not medical advice.

Back to Peripheral Neuropathy

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

You have been diagnosed with a hereditary condition called ATTRv-PN (a nerve disease caused by a faulty TTR gene that leads to abnormal protein build-up in the body)
You are able to carry out most normal daily activities — meaning your overall health and physical ability meet a minimum level as measured by a standard scoring tool (confirm with trial site)

Who may not be able to join:

Your amyloidosis (protein build-up disease) is caused by a protein other than TTR
You have nerve damage (affecting movement, feeling, or automatic body functions) caused by something other than ATTRv-PN
You have diabetes
You have moderate to severe heart failure (confirm with trial site)
You have liver failure
You have a current infection with hepatitis B, hepatitis C, or HIV
You have previously been treated with a type of gene-silencing drug for TTR, such as siRNA or ASO therapies (for example, patisiran or inotersen)
Your kidneys are not working well enough, based on a standard kidney function test result below a certain level (confirm with trial site)
You are unable or unwilling to take vitamin A supplements throughout the whole study
You have a history of liver disease

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.

Last synced 16 July 2026

Phase 3: approximately ~65% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.

Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Phone: 1-857-285-6200

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Voxsanity

Clinical trials and treatments, explained plainly · voxsanity.com.au

Date:

To: My Doctor

Re: Clinical trial enquiry

I am writing to enquire about the following clinical trial which may be relevant to my care:

Trial: NCT06672237

Sponsor: Intellia Therapeutics

Phase: Phase 3

Status: Recruiting

Condition: Peripheral Neuropathy

Trial contact: 1-857-285-6200

More information: https://clinicaltrials.gov/study/NCT06672237

Eligibility summary (AI generated)

Written by an AI model from the ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

You have been diagnosed with a hereditary condition called ATTRv-PN (a nerve disease caused by a faulty TTR gene that leads to abnormal protein build-up in the body)
You are able to carry out most normal daily activities — meaning your overall health and physical ability meet a minimum level as measured by a standard scoring tool (confirm with trial site)

Who may not be able to join:

Your amyloidosis (protein build-up disease) is caused by a protein other than TTR
You have nerve damage (affecting movement, feeling, or automatic body functions) caused by something other than ATTRv-PN
You have diabetes
You have moderate to severe heart failure (confirm with trial site)
You have liver failure
You have a current infection with hepatitis B, hepatitis C, or HIV
You have previously been treated with a type of gene-silencing drug for TTR, such as siRNA or ASO therapies (for example, patisiran or inotersen)
Your kidneys are not working well enough, based on a standard kidney function test result below a certain level (confirm with trial site)
You are unable or unwilling to take vitamin A supplements throughout the whole study
You have a history of liver disease

Important: Always verify eligibility with the trial site directly before applying.

Access in Australia: A treatment being studied in a clinical trial is generally not yet listed on the PBS. Where a medicine is not approved or not available through a trial, the TGA Special Access Scheme may allow a doctor to access unapproved therapeutic goods for individual patients. See voxsanity.com.au/sas-navigator/ for a plain English explainer.

This information was sourced from ClinicalTrials.gov via Voxsanity (data last synced 16 July 2026). It is not medical advice. Please verify the trial's current status directly with the trial site before acting.

Trial details

Status

Recruiting

Phase

Phase 3

Sponsor

Intellia Therapeutics

Registry

ClinicalTrials.gov

Start date

22 November 2024

Est. completion

1 July 2027

Where this trial is recruiting

🇦🇷 Argentina 🇧🇷 Brazil 🇲🇽 Mexico 🇸🇬 Singapore 🇹🇼 Taiwan 🇹🇭 Thailand

Primary endpoints

Modified Neuropathy Impairment Score +7 (mNIS+7); Serum TTR

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 16 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov