Phase 2 Parkinson's Disease Trial, Recruiting NCT06680830 Sponsor: Neuron23 Inc. Condition: Parkinson's Disease
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Phase 2 Parkinson's Disease Trial, Recruiting

NCT06680830
Recruiting Phase 2

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You are between 40 and 80 years old (inclusive) at the time of screening
  • You have been diagnosed with clinically established or clinically probable Parkinson's Disease
  • Your Parkinson's Disease is linked to a specific gene called LRRK2, confirmed through a special genetic test used in this trial
  • Your Parkinson's symptoms are in a mild to moderate range, based on a standard rating scale called the Modified Hoehn and Yahr scale (scores 1 to 2.5) (confirm with trial site)

Who may not be able to join:

  • You have a form of parkinsonism that is caused by another condition or is considered an atypical type, rather than standard Parkinson's Disease
  • You have diabetes that is not well controlled, shown by a blood sugar marker (HbA1c) above 8%
  • You have other serious health conditions identified through your medical history, physical examination, or tests done at screening (confirm with trial site)

Please note: There are additional eligibility requirements outlined in the full study protocol that are not listed here. These may apply depending on which part of the trial you are being considered for.

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 28 July 2026
Phase 2: approximately ~30% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: Fatta B Nahab, MD, FAAN FANA, Neuron23 Inc.

Phone: 650-228-2527

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 2
Sponsor
Neuron23 Inc.
Registry
ClinicalTrials.gov
Start date
17 January 2025
Est. completion
1 December 2027

Where this trial is recruiting

🇮🇱 Israel 🇮🇹 Italy 🇵🇱 Poland 🇪🇸 Spain 🇬🇧 United Kingdom 🇺🇸 United States

Primary endpoints

Change from baseline in the Roche digital biomarker score using the Roche Parkinson's Disease application (v3.0) compared to placebo; Incidence of treatment-emergent adverse events (TEAEs) and serious adverse events (SAEs) compared to placebo

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov