Phase 1 Parkinson's Disease Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- People who are already scheduled to undergo deep brain stimulation (DBS), a type of brain surgery used to treat movement disorders
- People who have been diagnosed with Parkinson's disease (PD) according to recognised medical guidelines (either a confirmed or highly likely diagnosis)
- People aged between 45 and 75 years old (inclusive)
- People who are healthy enough to safely go through the surgical procedure
- People who are able to complete all of the planned tests and assessments involved in the trial
- People who have a suitable sural nerve available (a nerve located in the lower leg) (confirm with trial site)
Who may not be able to join:
- People who have a health condition that would make them unsuitable for deep brain stimulation surgery
- People who have been diagnosed with dementia
- People who have previously had brain surgery or surgery related to Parkinson's disease
- People who are unable to have an MRI scan
- People whose brain anatomy does not allow a clear surgical path to the specific brain regions targeted in this trial (confirm with trial site)
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: Craig G van Horne, MD, PhD, University of Kentucky
Phone: 8593231908
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Successful deployment of bilateral peripheral nerve tissue (PNT) into the brain; Number of participants completing 12 month study visit; Study-related adverse events as assessed by MedDRA v27; Study-related serious adverse events as assessed by MedDRA v.27
Can't join this trial?
Data last synced from ClinicalTrials.gov: 19 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.