Phase 2 Lung Cancer Trial, Not Yet Recruiting NCT06746870 Sponsor: ImmuneOnco Biopharmaceuticals (Shanghai) Inc. Condition: Lung Cancer
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Phase 2 Lung Cancer Trial, Not Yet Recruiting

NCT06746870
Not Yet Recruiting Phase 2

voxsanity.com.au · Eligibility summary from public government registries · 18 August 2026 · not medical advice

Who may and may not be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who may be able to join

  • People who fully understand the study and are willing to sign the consent form voluntarily.
  • People aged 18 years or older.
  • People with a specific type of lung cancer (non-small cell lung cancer, or NSCLC) that does not have certain genetic markers (EGFR wild-type, and no ALK or ROS1 gene fusions) — this includes both non-squamous and squamous subtypes — OR people with a type of breast cancer that tests negative for oestrogen receptors, progesterone receptors, and HER-2 (sometimes called triple-negative breast cancer).
  • For the lung cancer group: people who have not previously received systemic treatment for advanced disease, OR if they had earlier treatment before or after surgery, at least 12 months must have passed before the cancer came back or spread. People in a special early safety portion of the trial must have already tried at least one standard treatment that did not work, or were unable to tolerate or were not suitable for it. The same rules apply to the breast cancer group, with the additional detail that if taxane-based chemotherapy was given before or after surgery, at least 12 months must have passed before the cancer returned or spread.
  • People with a performance status score of 0 or 1 on the ECOG scale, meaning they are able to carry out daily activities with little or no difficulty.
  • People who have at least one measurable tumour lesion as defined by standard imaging criteria (RECIST 1.1).
  • People with an expected survival of at least 12 weeks.
  • People able to provide tumour tissue samples — either stored samples or newly taken biopsy or surgical samples from a tumour site that has not been previously treated with radiation — for laboratory testing (confirm with trial site for specific sample requirements).
  • Women of childbearing potential who agree to use effective contraception during the study and for 6 months after the last dose, and who have a negative pregnancy test within 3 days before the first dose; male participants must also agree to use effective contraception during the study and for 6 months after the last dose.

Who may not be able to join

Each point below is a reason the trial team may not be able to accept someone. It is not a list of requirements to meet.

  • People who have received any approved or experimental anti-cancer treatment within 4 weeks before the start of the study treatment.
  • People who have received certain immune-boosting treatments within 2 weeks before the start of the study treatment.
  • People who have previously received any drug that targets PD-1, PD-L1, or VEGF (specific immune checkpoint or blood vessel pathways).
  • People with certain abnormal blood or laboratory test results (confirm with trial site for specific values).
  • People with a history of lung scarring (pulmonary fibrosis) or who currently have severely reduced lung function.
  • People with chronic health conditions that are not well controlled.
  • People who still have unresolved side effects from previous treatments.
  • People with brain metastases (cancer that has spread to the brain) that are not well controlled.
  • People with an active infection at the time of enrolment.
  • People with conditions that put them at increased risk of bleeding.

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 17 July 2026

GP referral letter

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Trial details

Status
Not Yet Recruiting
Phase
Phase 2
Sponsor
ImmuneOnco Biopharmaceuticals (Shanghai) Inc.
Registry
ClinicalTrials.gov
Start date
1 December 2024
Est. completion
1 November 2025

This date has passed while the registry still lists the trial as open to participants. Sponsors often update a trial's status without revising its projected end date, so it may well still be recruiting — but the record is out of date in at least one respect. Check with the study contact before relying on either.

Primary endpoints

To evaluate the preliminary clinical efficacy of IMM2510 for Injection in combination with chemotherapy as first-line treatment in patients with stage IV metastatic or recurrent non-small cell lung cancer (NSCLC); To evaluate the preliminary clinical efficacy of IMM2510 for Injection in combination with nab-paclitaxel as first-line treatment in patients with unresectable locally advanced or metastatic triple-negative breast cancer (TNBC)

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 17 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov