Phase 2 Lung Cancer Trial, Not Yet Recruiting NCT06752408 Sponsor: Peking Union Medical College Hospital Condition: Lung Cancer
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Phase 2 Lung Cancer Trial, Not Yet Recruiting

NCT06752408
Not Yet Recruiting Phase 2

voxsanity.com.au · Eligibility summary from public government registries · 18 August 2026 · not medical advice

Who may and may not be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who may be able to join

  • People who are at least 18 years old.
  • People who have voluntarily signed a consent form before taking part in the study.
  • People whose physical functioning is rated 0 or 1 on a standard cancer performance scale (meaning they are fully active or have only minor limitations), with no worsening in the week before treatment, and who are expected to live at least 12 weeks.
  • People who have been confirmed through tissue or cell testing to have advanced or metastatic non-small cell lung cancer (stage IIIB–IV) that cannot be cured with current treatments.
  • People whose lung cancer has a specific gene change (EGFR mutation — either L858R or 19Del) confirmed through testing of tissue or body fluids such as blood, fluid around the lungs, abdominal fluid, or spinal fluid.
  • People who have not previously received systemic treatment for their cancer, except where treatment was given before or after surgery, and only if the cancer did not return within 6 months of that treatment ending.
  • People who have at least one measurable tumour in the lung that has not been treated with radiation, measuring at least 10 mm at its longest point (or at least 15 mm for lymph nodes), as assessed using standard imaging guidelines.

Who may not be able to join

Each point below is a reason the trial team may not be able to accept someone. It is not a list of requirements to meet.

  • People who have cancer that has spread to the membranes surrounding the brain or spinal cord, or who have both brain tumours and this type of membrane involvement.
  • People who have a history of another separate type of cancer.
  • People who have a known allergy or sensitivity to the study drugs (aumolertinib or osimertinib) or any of their ingredients.
  • Women who are pregnant, breastfeeding, or planning to become pregnant during the treatment period.
  • People whose overall health conditions — such as poorly controlled high blood pressure or active bleeding — may put them at risk or affect how the study results are assessed, as determined by the treating doctor (confirm with trial site).

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 15 July 2026

Contact this trial

Phone: 010-69155039

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Not Yet Recruiting
Phase
Phase 2
Registry
ClinicalTrials.gov
Start date
17 December 2024
Est. completion
16 January 2027

Where this trial is recruiting

🇨🇳 China

Primary endpoints

Progression Free Survival (PFS) as Assessed by Investigator Per Response Evaluation Criteria in Solid Tumors (RECIST) v1.1

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 15 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov