Phase 1 Type 1 Diabetes Trial, Recruiting NCT06753994 Sponsor: McGill University Condition: Type 1 Diabetes
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Phase 1 Type 1 Diabetes Trial, Recruiting

NCT06753994
Recruiting Phase 1

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • Adults aged 18 or older.
  • People who have been diagnosed with Type 1 diabetes for at least one year, as confirmed by their treating doctor.
  • People whose HbA1c blood sugar level has been below 11% at some point in the last six months.
  • People who are currently using intensive insulin therapy — either multiple daily injections or a closed-loop insulin pump — and do not plan to change this during the study.
  • People who are currently using a continuous glucose monitor (CGM), either one that shows readings in real time or one that is scanned intermittently.
  • People who are actively avoiding pregnancy during the trial, including using effective contraception if sexually active and capable of becoming pregnant.
  • People who are able to eat an average of more than 50 grams of carbohydrates per day.
  • People who own a compatible smartphone that can run the study's sensor application.

Who may not be able to join:

  • People who have had a diabetic ketoacidosis (DKA) episode or a severe low blood sugar episode in the last six months.
  • People who are currently using, or have recently used, any blood sugar-lowering medication other than insulin — within the last month for GLP-1 receptor agonists, or within the last week for other types.
  • People who are currently using, or have used within the last month, high-dose steroid (glucocorticoid) medication above normal body levels.
  • People with a body mass index (BMI) below 20 kg/m².
  • People whose kidney filtration function (eGFR) is below 30 mL/min/1.73 m², based on a blood test taken within the last two months (confirm with trial site).

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 7 July 2026
Phase 1: approximately ~10% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: Michael Tsoukas, M.D., Clinique Medicale Hygea

Phone: 5144045621

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 1
Sponsor
McGill University
Registry
ClinicalTrials.gov
Start date
5 December 2024
Est. completion
1 January 2027

Where this trial is recruiting

🇨🇦 Canada

Primary endpoints

Number of events ≥ 0.6 mmol/L, ≥ 0.8 mmol/L ≥ 1.5 mmol/L, ≥ 3.0 mmol/L that last for more than one hour

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 7 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov