Phase 2 Myeloma Trial, Recruiting

Written by an AI model from the ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• People aged between 18 and 70 years old
• People with an expected survival of more than 12 weeks
• People who have been diagnosed with multiple myeloma through physical examination, lab tests, imaging, and tissue analysis
• People whose multiple myeloma has not responded to treatment (refractory)
• People whose multiple myeloma has come back after treatment (relapsed)
• People whose liver enzyme levels (ALT and AST) are below 3 times the normal range
• People whose bilirubin level is below 2.0 mg/dl
• People with a quality of life/function score (KPS) above 50%, meaning they are able to carry out at least some daily activities (confirm with trial site)
• People who do not have serious heart, liver, kidney, or other major organ disease
• People whose myeloma returned or did not go into remission after a stem cell transplant or cellular immune therapy
• People who are not suitable for stem cell transplantation, or for whom transplantation is not possible due to other limitations
• People from whom blood can be collected through a vein, with no medical reasons preventing a leukapheresis procedure (a process where certain blood cells are separated and collected)
• People who understand the trial and have voluntarily signed a written consent form

Who may not be able to join:

• People who are pregnant, breastfeeding, or planning to become pregnant within six months
• People with certain infectious diseases, such as HIV or active tuberculosis
• People with an active hepatitis B or hepatitis C infection
• People whose blood cells showed poor results during a pre-screening test — specifically, less than 10% of the targeted white blood cells were successfully modified, or the cells did not multiply sufficiently during laboratory preparation (confirm with trial site)
• People with abnormal vital signs who are unable to cooperate with medical examinations
• People with a mental health condition that would prevent them from cooperating with treatment or assessments
• People with a highly allergic history or a known severe allergy, particularly to a substance called IL-2
• People who have a widespread infection throughout the body, or a severe local infection currently requiring treatment
• People with a serious autoimmune disease
• People who the treating doctor considers unsuitable for the trial for other medical reasons

Important: Always verify eligibility with the trial site directly before applying.