Phase 2 Pancreatic Cancer Trial, Recruiting

Written by an AI model from the ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• People aged 18 to 75 years, of any gender
• People who have been diagnosed with locally advanced or metastatic pancreatic cancer through a tissue or cell sample test
• People who have not yet received any cancer treatment
• People who have at least one tumour that can be measured on a scan, according to standard measurement guidelines
• People with a good general level of physical functioning (able to carry out daily activities with little or no limitation)
• People with an expected survival of at least 3 months
• People without serious disease affecting the heart, lungs, brain, liver, kidneys, or other major organs
• Women of childbearing age who are willing to use contraception during treatment and for 6 months after treatment ends, who are not pregnant (confirmed by a blood or urine test within 7 days before joining), and who are not breastfeeding
• Men who are willing to use contraception during the study and for 6 months after it ends

Who may not be able to join:

• People who have already received or are currently receiving cancer treatments such as chemotherapy, radiotherapy, targeted therapy, immunotherapy, or traditional Chinese medicine for cancer
• People with a known allergy to any of the study drugs
• People with brain metastases causing symptoms, or whose brain metastases have only been controlled for less than 2 months
• People whose cancer has spread to more than 70% of the liver
• People with jaundice caused by a blockage where bilirubin levels cannot be adequately reduced even after treatment to relieve the blockage
• People with active autoimmune diseases, or conditions expected to flare up again (such as lung inflammation, bowel inflammation, liver inflammation, or other immune-related conditions)
• People with a history of immune system deficiency, or who are currently using medications that suppress the immune system, including steroids
• People with known bleeding disorders or blood clotting conditions (such as haemophilia), or those who have recently used full-dose blood-thinning or clot-dissolving medications within 10 days before starting the study (preventive low-dose aspirin or low molecular weight heparin is allowed)
• People who have had a serious infection within 4 weeks before starting the study, or who show signs of an active infection or are taking antibiotic treatment within 2 weeks before starting (unless antibiotics are being used only for prevention)
• People who have had another cancer in the past 5 years or currently have another cancer, except for certain treated skin cancers, cervical carcinoma in situ, or papillary thyroid carcinoma
• People with a mental illness, or a history of misuse of alcohol, recreational drugs, or psychoactive substances
• Women who are pregnant or breastfeeding
• People considered unsuitable for the trial by the research team for other reasons (confirm with trial site)

Important: Always verify eligibility with the trial site directly before applying.