Phase 3 Depression and Anxiety Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- Adults aged 18 to 74 whose first episode of major depression began before the age of 50
- People with a Body Mass Index (BMI) of 40 or below
- People who currently meet the formal medical diagnosis criteria for major depressive disorder (MDD), confirmed through a structured psychiatric interview
- People whose current depressive episode has lasted at least 6 weeks but no longer than 24 months
Who may not be able to join:
- People whose primary mood disorder diagnosis is something other than MDD
- People with a history of MDD with psychotic or catatonic features, MDD with mixed features, Bipolar I or II disorder, obsessive-compulsive disorder, schizophrenia, or other psychotic disorders
- People currently diagnosed with seasonal depression, depression related to childbirth or menopause, post-traumatic stress disorder, antisocial or borderline personality disorder, panic disorder, agoraphobia, or ADHD that is treated with stimulant medication, was diagnosed during the current depressive episode, or has unstable symptoms (confirm with trial site)
- People who have had a problem with alcohol or drug use (not including tobacco) in the past 12 months
- People who have had an active plan or intent to end their life in the past 6 months, any suicidal behaviour in the past 2 years, or more than one suicide attempt after the age of 24
- People who have deliberately harmed themselves (without suicidal intent) in the past 12 months
- People who have taken antidepressants or certain other restricted medications, including benzodiazepines, within the past 2 weeks (or 4 weeks for the antidepressant fluoxetine), or within a specific medication clearance period — whichever is longer (confirm with trial site)
- People whose depression did not respond to two or more antidepressant medications at appropriate doses and durations during the current depressive episode
- People with other medical conditions that could interfere with the study (confirm with trial site)
- People who are pregnant, breastfeeding, or planning to become pregnant
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Phone: 1-604-484-3300
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Change from baseline in the Hamilton Depression Rating Scale, 17-item (HAMD-17) score at Week 6
Can't join this trial?
Data last synced from ClinicalTrials.gov: 21 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.