Parkinson's Disease Trial, Recruiting NCT06778135 Sponsor: University of Colorado, Denver Condition: Parkinson's Disease
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Parkinson's Disease Trial, Recruiting

NCT06778135
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who have been diagnosed with Parkinson's disease and whose symptoms are not well controlled by medication, making them a candidate for deep brain stimulation surgery.
  • People between the ages of 45 and 85.
  • People who are able to give their informed consent to participate.
  • People whose mental and cognitive health assessment shows no more than mild impairments, which would be considered within the expected range for someone with Parkinson's disease.
  • People who a study neurosurgeon has assessed as medically suitable to undergo deep brain stimulation surgery.
  • People whose surgical plan allows for a safe entry point in a specific area at the front of the brain (confirm with trial site for details).
  • People who are able to be awake during the deep brain stimulation surgery, as planned by their medical team.
  • People who are able to tolerate approximately 25 extra minutes of being awake during surgery.
  • People who are able to follow instructions given in English and participate in study tasks.

Who may not be able to join:

  • People who have been assessed by a licensed neuropsychologist as having moderate or severe cognitive impairment.
  • People who a treating neurologist and study neurosurgeon have determined cannot safely be awake during surgery.
  • People whose brain anatomy does not allow safe surgical access to the specific area of the brain required for this trial.
  • People who show moderate or severe cognitive impairment or significant difficulties with thinking and planning tasks, based on neuropsychological testing.
  • People whose pre-surgery brain imaging shows a significant abnormality.

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 23 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Phone: 303-724-4134

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Registry
ClinicalTrials.gov
Start date
25 July 2025
Est. completion
1 October 2027

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Measure the neural population representations of task parameters along, and within, the cortical layers.

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 23 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov