Phase 3 Depression and Anxiety Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- People who have been diagnosed with recurring moderate or severe major depression, or long-lasting (persistent) depression.
- People whose current episode of depression has not improved enough with oral antidepressant tablets.
- People who have been taking oral antidepressant tablets for at least 8 weeks and are willing to keep taking the same medication at the same dose throughout the study.
- People who score 22 or higher on a standard depression rating scale (called the HAM-D17) at two early points in the study process.
- People who, in the opinion of the trial team, are willing and able to follow all study procedures and requirements.
Who may not be able to join:
- People who have been diagnosed with, or treated for, another mental health condition as their main focus of care within the past year (other than depression).
- People whom the trial team considers to be at immediate risk of harming themselves or others.
- People whose depression did not respond to electroconvulsive therapy (ECT) during the current episode of depression.
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: Clinical Development Lead, Neurocrine Biosciences
Phone: 1-877-641-3461
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Change from Baseline in Total Montgomery-Åsberg Depression Rating Scale (MADRS) Score at Day 56
Can't join this trial?
Data last synced from ClinicalTrials.gov: 26 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.