Colorectal Cancer Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• People of any gender
• People who self-identify as Alaska Native or American Indian and are eligible for care at the Alaska Native Medical Center (ANMC)
• People aged 21 years or older
• People with rectal cancer (Stage II, III, or IV if treatment is aimed at cure) confirmed by tissue testing, who are receiving treatment before surgery (neoadjuvant)
• People with HER2-positive or triple-negative breast cancer (Stage I, II, or III) confirmed by tissue testing, who are receiving treatment before surgery (neoadjuvant)
• People with a solid tumour confirmed by tissue or cell testing, who are receiving treatment after surgery (adjuvant)
• People with a Body Mass Index (BMI) of 18.5 or above — a measure of body weight relative to height
• People who are planned to receive cancer treatment either before or after surgery
• People whose planned treatment is expected to last more than 3 months
• People who are able to understand the study and give their own informed consent
• People who are willing and able to follow the study schedule, visits, and requirements
• People who have completed no more than 4 weeks of their current cancer treatment before joining the study
• People who score below 4 on a standard food security questionnaire, or who score 5 or above and have received clearance from a dietitian (confirm with trial site)

Who may not be able to join:

• People who received certain chemotherapy within 12 months before their rectal or breast cancer diagnosis (for those in the pre-surgery treatment group)
• People with a known allergic reaction to any of the treatment agents used in the study
• People who have previously had radiotherapy to the pelvis area
• People with an active second cancer currently requiring systemic (whole-body) treatment — though certain skin cancers and a type of cervical pre-cancer that has been treated may be acceptable
• People with a history of a hole or tear in the gut (gastrointestinal perforation) within the past 12 months
• People with a pre-existing condition affecting the bowel or small intestine, with severe or rapidly worsening symptoms unrelated to their current cancer
• People who are receiving nutrition through a drip, a feeding tube, or a similar nutritional supplement during the study period
• People with poorly controlled heart failure classified as NYHA Class III or higher — a medical grading of heart failure severity (confirm with trial site)
• People with pre-existing nerve damage rated at Grade 3 or above — a medical scale for nerve-related side effects (confirm with trial site)
• People who are currently in, or have recently participated in, another study involving an experimental treatment within the past 4 weeks
• People with unstable mental health, sleep, or body-clock conditions — though common conditions like sleep apnoea or depression may be acceptable if they are stable and not getting worse quickly
• People who are pregnant or breastfeeding
• People who currently work overnight shifts more than one night per week
• People who are already strictly limiting their eating to a window of less than 10 hours on most days
• People with severe psychiatric, thinking, or substance use difficulties, or social circumstances that would make it hard to follow study procedures

Important: Always verify eligibility with the trial site directly before applying.