Depression and Anxiety Trial, Recruiting

Written by an AI model from the ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• Adults between 18 and 40 years old who do not have depression
• Adults between 18 and 40 years old who have been clinically diagnosed with major depressive disorder (MDD) and are not currently taking any antidepressant medication
• Adults between 18 and 40 years old who have been clinically diagnosed with MDD and have been taking an SSRI-type antidepressant for at least 2 weeks
• Adults between 18 and 40 years old who have been clinically diagnosed with MDD and have been taking an SNRI-type antidepressant for at least 2 weeks
• People who have no current symptoms or warning signs such as chest pain, dizziness, joint pain, or signs of heart disease, based on standard exercise safety guidelines
• People whose blood pressure readings at screening are at or below 140 (systolic) over 90 (diastolic)
• People who do not have diabetes
• People who are not taking other medications that could affect the body's physical responses being studied, such as beta blockers, certain older antidepressants, fever-reducing medicines, or water pills
• People whose aerobic fitness level falls between the 20th and 80th percentile for their age and sex, based on standard fitness assessment guidelines (confirm with trial site)
• People who are proficient in English
• People who are able to understand and sign a consent form

Who may not be able to join:

• People with a BMI over 35
• People who are pregnant or planning to become pregnant within the next 12 months
• People who are currently taking part in another study involving physical activity or weight loss
• People who plan to have surgery or move out of the area within the next year
• People taking medications that could affect how the heart or body temperature responds to exercise, such as beta blockers, fever-reducing medicines, certain older antidepressants, or water pills
• People with an allergy to latex or adhesive materials
• People who use tobacco products
• People who use illegal or recreational drugs
• People who experience chest pain or muscle or joint pain during physical activity
• People who have a medical reason that would prevent them from safely completing a maximum-effort exercise test, based on standard exercise safety guidelines (confirm with trial site)
• People who have an abnormal heart rhythm reading at rest or during exercise
• People with bleeding disorders, stomach ulcers, allergies to anti-inflammatory pain medicines (such as ibuprofen), asthma, kidney or liver problems, or who are taking blood-thinning medications
• People with a history of Crohn's disease, diverticulitis, or similar bowel conditions
• People who have been diagnosed with another psychiatric condition such as psychosis, schizophrenia, bipolar disorder, panic disorder, or obsessive compulsive disorder
• People who are currently experiencing moderate to high levels of suicidal thoughts
• People who have used mind-altering or psychiatric medications — other than SSRIs or SNRIs — within the past year

Important: Always verify eligibility with the trial site directly before applying.