Phase 4 Depression and Anxiety Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• People aged 18 or older
• People who have had a caesarean delivery (planned or emergency)
• People who gave birth at 32 weeks of pregnancy or later
• People whose haemoglobin (a measure of red blood cells) was measured within 72 hours after birth and fell within a specific moderate range — not too low, not normal (confirm with trial site for exact values)
• People whose iron stores (measured by ferritin level or transferrin saturation — two types of iron blood tests) are below a certain threshold, tested after the haemoglobin measurement
• People who scored below 11 on a postnatal mood questionnaire (called the EPDS) shortly after birth, and answered "never" to question 10 of that questionnaire
• People who have signed a consent form agreeing to take part
• People staying in the postnatal maternity ward
• People covered by French national social security, including AME (a form of French health coverage)

Who may not be able to join:

• People whose baby was stillborn or died shortly after birth
• People whose recorded body weight (measured late in pregnancy or after birth) was below 35kg or above 100kg
• People with Biermer disease (a condition affecting vitamin B12 absorption)
• People with haemochromatosis (a condition causing the body to store too much iron)
• People with homozygous sickle cell disease or thalassaemia (inherited blood disorders)
• People who were taking iron supplements regularly before pregnancy (not as part of pregnancy care)
• People with a known allergy or sensitivity to the iron treatments being studied (whether given by injection or by mouth)
• People for whom the iron treatments being studied (injectable or oral iron) are medically unsuitable
• People with severe asthma requiring daily ongoing medication
• People with a known serious kidney or liver condition
• People with an active infection at the time of joining
• People with a diagnosis of schizophrenia, or whose physical or intellectual condition would make it difficult to reliably complete self-assessment questionnaires
• People currently receiving medication or electroconvulsive therapy (ECT) for depression or bipolar disorder
• People already participating in another clinical trial that could affect haemoglobin levels at 2 months after birth, affect EPDS mood scores at 2 or 6 months after birth, or that involves a treatment with a risk of serious allergic reaction given during the postnatal hospital stay
• People who do not have a sufficient understanding of the French language
• People under legal guardianship or a formal protection order (curatorship or tutorship)

Important: Always verify eligibility with the trial site directly before applying.