Phase 2 Lung Cancer Trial, Not Yet Recruiting NCT06837948 Sponsor: Shanghai Pulmonary Hospital, Shanghai, China Condition: Lung Cancer
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Phase 2 Lung Cancer Trial, Not Yet Recruiting

NCT06837948
Not Yet Recruiting Phase 2

voxsanity.com.au · Eligibility summary from public government registries · 18 August 2026 · not medical advice

Who may and may not be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who may be able to join

  • The person must be willing and able to sign a consent form agreeing to take part in the trial.
  • The person must be 18 years of age or older.
  • The person must have a confirmed diagnosis of non-small cell lung cancer (NSCLC) through a tissue or cell sample taken by needle, with the cancer at stage II or III as confirmed by scans (such as CT or PET-CT), and must not have received any cancer treatment before.
  • The person must have a good general level of physical functioning, rated 0 or 1 on a standard medical scale (meaning fully active or able to carry out light activity).
  • The person must be expected to live for at least 12 weeks.
  • The person must have at least one area of cancer that can be measured on scans, according to standard measurement guidelines.
  • The person must have adequately functioning major organs, including the liver, kidneys, and blood system.
  • The person must have lung function that is strong enough to tolerate surgery.
  • The cancer must not have spread to other parts of the body.
  • Women who are able to become pregnant must agree to use effective contraception throughout the study and for at least 120 days after completing chemotherapy or the last dose of the study drug (whichever comes later), and must have a negative pregnancy test within 7 days before joining.
  • Men who have not been surgically sterilised must agree to use effective contraception throughout the study and for at least 120 days after completing chemotherapy or the last dose of the study drug (whichever comes later).

Who may not be able to join

Each point below is a reason the trial team may not be able to accept someone. It is not a list of requirements to meet.

  • People diagnosed with lung adenocarcinoma that has confirmed EGFR mutations or ALK rearrangements (specific genetic changes in the cancer).
  • People whose tissue samples show any small cell lung cancer components.
  • People who have had another type of cancer within the past five years.
  • People who have already received any treatment for NSCLC, including surgery, radiation therapy, chemotherapy, targeted therapy, or any experimental treatment.
  • People who have certain serious ongoing health conditions, including active infections, poorly controlled high blood pressure, unstable chest pain (angina), chest pain that began within the last 3 months, moderate to severe heart failure, a heart attack within the past 6 months, serious irregular heart rhythms requiring medication, or significant liver, kidney, or metabolic diseases.
  • People with an active or suspected autoimmune disease, or a nerve or muscle condition related to cancer that requires treatment affecting the whole body.
  • People who are allergic to the trial drug.
  • People currently diagnosed with interstitial lung disease (a condition causing scarring or inflammation in the lungs).
  • People with HIV infection or active hepatitis.
  • Women who are pregnant or breastfeeding.
  • People with neurological or psychiatric conditions that would prevent them from cooperating with the trial.
  • People who are currently taking part in another treatment-based clinical trial.
  • People considered unsuitable for the trial for any other reason, as determined by the trial doctor.

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 24 July 2026

Contact this trial

Principal Investigator: Peng Zhang, PhD, Shanghai Pulmonary Hospital, Shanghai, China

Phone: 02165115006

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Not Yet Recruiting
Phase
Phase 2
Sponsor
Shanghai Pulmonary Hospital, Shanghai, China
Registry
ClinicalTrials.gov
Start date
18 February 2025
Est. completion
1 December 2031

Where this trial is recruiting

🇨🇳 China

Primary endpoints

Pathologic complete response (PCR) rate

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 24 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov