Pancreatic Cancer Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• People aged 18 to 80 years old
• People who have been diagnosed with locally advanced or spreading (stage III or IV) pancreatic cancer, confirmed through a tissue or cell sample test
• People who have at least one tumour that can be measured on a scan, according to standard measurement guidelines
• People who are suitable to receive one cycle of a specific chemotherapy combination (gemcitabine and nituzumab)
• People who have not had another type of cancer in the past, except for fully cured skin cancer or very early-stage cervical cancer (stage 0)
• People whose liver, kidney, and blood cell levels are within an acceptable range (confirmed with trial site for specific values)
• People who are in reasonably good physical health, able to carry out basic daily activities, and have no serious heart or lung conditions that could interfere with radiation treatment
• People whose major organs are functioning adequately
• People whose expected survival after treatment is at least 3 months
• People (or their legal representative) who have signed a consent form before radiation treatment begins

Who may not be able to join:

• People who have received certain targeted or immune-suppressing treatments (monoclonal antibodies, EGFR-TKI therapy, anti-angiogenic drugs, or immunosuppressants) within the past six months
• People who have uncontrolled fluid build-up around the lungs, heart, or in the abdomen requiring frequent draining, active gastrointestinal bleeding, or a high bleeding risk in the 14 days before joining
• People who have taken part in another interventional clinical trial within the past 30 days
• People whose radiation dose to surrounding healthy organs cannot be kept within safe limits
• People who have been taking steroid medication long-term (more than 6 months) at doses above a certain level (confirm with trial site for specific dose details)
• People who are allergic to any of the medications or their ingredients used in this trial
• People who are pregnant (confirmed by a blood or urine test) or currently breastfeeding
• People living with HIV/AIDS, including those on antiretroviral therapy, or people with active syphilis
• People with serious uncontrolled health conditions such as heart, lung, liver, kidney, or blood sugar problems, or those with drug, alcohol, or mental health conditions that could prevent them from completing the trial
• People who are unlikely to be able to follow the full treatment plan or attend required follow-up appointments
• People who have or have had another type of cancer (except fully cured skin cancer or very early-stage cervical cancer)
• People who have any medical reason that makes radiation treatment unsuitable
• People who do not have the legal capacity to make their own decisions (confirm with trial site)
• People with any medical history that, in the doctor's judgement, could affect the trial results or raise their risk
• People whose doctor believes they would not benefit from carbon ion radiation therapy, or where other health factors make participation unsuitable
• People who do not understand the purpose of the treatment or are unwilling or unable to sign a consent form

Important: Always verify eligibility with the trial site directly before applying.