Hypertension Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• People aged 22 or older, of any gender
• People who have been diagnosed with elevated blood pressure or high blood pressure, confirmed by a seated arm cuff measurement at the first visit
• People who have not taken any blood pressure-lowering medications for at least 30 days before the screening visit
• People who have adequate vision, hearing, and hand strength — specifically, hand strength must reach at least 35 units of force in both hands, as measured by a grip-strength device
• People whose baseline blood pressure readings are collected and who complete training on the study device at the first visit
• People who agree not to start or change any medications or over-the-counter supplements related to blood pressure during the treatment period
• People who are able and willing to attend all required study visits and complete all study activities
• People who can understand and sign a written consent form in the language provided
• People whose seated systolic blood pressure (the top number) is between 130 and 149 mmHg — those at 140 mmHg or above will be monitored more closely during the first month

Who may not be able to join:

• Women who could become pregnant and are not using an effective form of birth control, or who are currently pregnant, breastfeeding, or planning to become pregnant during the study
• People whose blood pressure is 150 mmHg or higher (top number) and/or above 90 mmHg (bottom number)
• People with a history of heart failure that is currently classified as severe (NYHA Class III or IV)
• People who have a history of, or currently have, atrial fibrillation (an irregular heart rhythm condition)
• People who have been hospitalised in the past 6 months due to a serious blood pressure emergency involving damage to organs such as the kidneys, heart, or brain
• People whose blood pressure readings differ by more than 10 mmHg between the left and right arms at the screening visit
• People whose blood pressure is considered unstable — meaning it varies by more than 5 mmHg between consecutive weekly readings taken to establish a starting measurement
• People whose upper arm circumference is greater than 45 cm
• People who currently have an acute illness, infection, or inflammation
• People who have had a serious heart or blood vessel event — such as a heart attack, unstable chest pain, significant abnormal heart rhythm, stroke, or mini-stroke — within the past 6 months, or who have another serious health condition likely to affect life expectancy or study participation
• People who have experienced chest pain at rest or during activity in the past 6 months
• People who have had a solid organ transplant (such as a kidney, liver, or heart transplant)
• People whose high blood pressure is caused by another underlying medical condition, such as a hormone disorder, steroid use, a tumour affecting the adrenal gland, a narrowing of the main heart artery, or untreated thyroid or parathyroid disease
• People who are currently participating in another clinical trial that has not yet finished, or who plan to join another study within the next 6 months
• People who, in the opinion of the study investigator, have any other condition or circumstance that could affect the quality of data collected or their ability to complete the study
• People who currently own, or have previously owned, a Zona Plus device and have been using it for isometric handgrip exercises
• People who plan to lose or gain more than 10% of their body weight over the course of the 6-month study

Important: Always verify eligibility with the trial site directly before applying.