Phase 2 Depression and Anxiety Trial, Recruiting NCT06846320 Sponsor: AbbVie Condition: Depression and Anxiety
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Phase 2 Depression and Anxiety Trial, Recruiting

NCT06846320
Recruiting Phase 2

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who have been formally diagnosed with Generalized Anxiety Disorder (GAD), confirmed through a structured medical interview called the MINI.
  • People who are currently taking an antidepressant medication for GAD as specified by the trial, have been taking it at the recommended dose for at least 8 weeks, and their anxiety has not improved enough — confirmed through scores on two standard anxiety rating scales completed at the start of the trial.

Who may not be able to join:

  • People whose score on a standard depression rating scale (called the MADRS) is 20 or higher, indicating significant depression symptoms.
  • People who have been newly diagnosed with major depression, or whose depression has significantly worsened, within the past 6 months.

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 27 July 2026
Phase 2: approximately ~30% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: ABBVIE INC., AbbVie

Phone: 844-663-3742

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 2
Sponsor
Registry
ClinicalTrials.gov
Start date
29 April 2025
Est. completion
1 November 2026

Where this trial is recruiting

Puerto Rico 🇺🇸 United States

Primary endpoints

Number of Participants with Adverse Events (AEs); Change from Baseline in the Hamilton Anxiety Scale (HAM-A) Total Score

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 27 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov