Parkinson's Disease Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

For Alzheimer's disease:

• You are male or female, between 50 and 75 years old
• You or your legal representative has signed and dated a consent form agreeing to take part
• You have been diagnosed mainly with mild memory and thinking problems or dementia caused by Alzheimer's disease
• A special brain scan (amyloid PET scan) has shown a positive result for Alzheimer's-related protein buildup in the brain
• Your score on a depression assessment (HAMD) is 17 or below, meaning depression is absent or mild
• Your score on a test that helps tell Alzheimer's from other causes of memory loss (Hachinski score) is 4 or below
• You meet certain general health standards for medical procedures (ASA grade I–III) (confirm with trial site)

For Parkinson's disease:

• You are male or female, between 50 and 80 years old
• You or your legal representative has signed and dated a consent form agreeing to take part
• You have been diagnosed with Parkinson's disease or probable Parkinson's disease based on recognised diagnostic guidelines
• Your Parkinson's symptoms are rated at stage I–IV on a standard scale measuring how much the disease affects movement and daily life
• You have had a documented history of Parkinson's disease for between 2 and 5 years or more, to confirm a stable diagnosis

Who may not be able to join:

• You cannot have an MRI scan, a certain type of eye/vessel imaging (ICG angiography), or a PET scan for any reason
• You cannot safely have a lumbar puncture (a procedure to collect fluid from around the spine)
• You have serious problems with a major organ, such as your heart, lungs, kidneys, or liver
• A recent MRI scan has shown active or serious brain problems, such as an infection, a tumour, significant bleeding, or multiple small bleeds in the brain
• You have a blood or clotting disorder that raises your risk of bleeding in the brain
• You have a thyroid condition that is not well controlled
• You have a disease affecting the blood vessels in your brain or throughout your body
• You have serious heart disease or an unstable heart condition
• You have severely high blood pressure that is not under control
• You have a problem with substance use, including illegal drugs, certain medications, or alcohol dependence
• You have an active serious infection, including HIV, or a critical acute infection
• You have a severe mental health condition or a significant risk of suicide
• You regularly use sleeping tablets or sedatives more than twice a week for over a month
• You have a cancer that has not been treated or fully cleared
• You have taken part in another interventional clinical trial in the last 3 months
• You are unable or unwilling to attend the follow-up appointments scheduled after the procedure
• There are other reasons the trial investigators decide make participation unsuitable for you (confirm with trial site)

Important: Always verify eligibility with the trial site directly before applying.