Colorectal Cancer Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- People aged 18 years or older
- People who have been diagnosed with locally advanced rectal cancer (a type of bowel cancer) confirmed by a tissue sample, where treatment guidelines recommend a combination of chemotherapy and radiotherapy before surgery
- People whose overall health is considered suitable for receiving chemotherapy at the same time as radiotherapy
- People whose cancer is small enough to fit within the treatment area of the specialist MRI-guided radiotherapy machine used in this trial
- People whose general health and activity level falls within an acceptable range (rated 0–2 on a standard medical scale, meaning someone is fully active to someone who is unable to do heavy physical work but can care for themselves)
- People who are willing and able to understand and sign a consent form agreeing to take part
- People who are willing and able to complete health and wellbeing questionnaires throughout the study
Who may not be able to join:
- People who cannot have an MRI scan — for example, those with a pacemaker, certain metal implants in the body, or severe claustrophobia (fear of enclosed spaces)
- People whose cancer has spread beyond what the radiotherapy machine can cover
- People with certain other health conditions that would significantly increase the risk of serious side effects (for example, inflammatory bowel disease), or that would prevent long-term follow-up
- People who have had a full hip replacement on one or both sides, or other metal implants in the pelvis that would interfere with the type of MRI scan used in this trial
- People who have previously had radiotherapy to the pelvic area
- People who need to receive chemotherapy on its own before starting the combined chemotherapy and radiotherapy treatment
- People who have had another type of cancer in the last 2 years — though some exceptions may apply, such as certain skin cancers, a specific low-risk type of bladder cancer (where recent checks have come back clear), or small kidney growths being monitored but not treated (confirm with trial site)
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Phone: extension 4228
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Number of patients completing 90% or more fractions delivered on MR-Linac.
Can't join this trial?
Data last synced from ClinicalTrials.gov: 6 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.