Hypertension Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
For healthy volunteers (control group):
- People aged 18 or older
- People attending a routine eye clinic appointment with dilating eye drops for an OCT scan, who are presumed to have normal pressure in the brain
For patients scheduled for a lumbar puncture or brain pressure monitoring:
- People aged 18 or older
- People already scheduled to have a lumbar puncture (spinal tap) where the pressure of the fluid around the brain and spine will be measured
- People already scheduled to have continuous monitoring of pressure inside the skull
Who may not be able to join:
For healthy volunteers (control group):
- People whose eyes have significant cloudiness or obstruction that would prevent clear imaging of the retinal veins in both eyes
- People who have, or have had, glaucoma, are suspected of having glaucoma, have a parent or sibling with glaucoma, or have damage to the optic nerve (unrelated to glaucoma) in both eyes
- People who have had a blockage of a vein or artery in the retina in both eyes
- People who have, or have had, advanced diabetic eye disease affecting the retina or optic nerve in both eyes
- People who show signs or symptoms that, in the investigator's opinion, suggest possibly raised pressure inside the skull
- People who have, or have had, conditions that affect brain pressure — including but not limited to idiopathic intracranial hypertension, fluid on the brain (hydrocephalus), epilepsy, bleeding in the brain, brain tumours or growths, traumatic brain injury, inflammatory or infectious brain conditions, certain birth-related brain or skull disorders, or any prior brain surgery or related procedures (note: a confirmed ischaemic stroke may be permitted, provided it was not followed by a bleed in the brain or brain surgery — confirm with trial site)
- People who have taken, or have taken within the past 6 months, certain medications known to affect brain pressure, including steroids, vitamin A-related drugs, certain antibiotics (such as tetracyclines, nitrofurantoin, nalidixic acid), recombinant growth hormone, lithium, sulfenazone, cyclosporine, or amiodarone
- People who are confined to bed
- People who, in the investigator's opinion, would be unwilling or unable to give written consent or complete the study procedures
For patients scheduled for a lumbar puncture or brain pressure monitoring:
- People who have, or have had, glaucoma or are suspected of having glaucoma in both eyes
- People who have had a blockage of a vein or artery in the retina in both eyes
- People who are confined to bed
- People who, in the investigator's opinion, would be unwilling or unable to give written consent or complete the study procedures
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Phone: +44 203 299 7791
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
• To acquire a multimodal dataset of clinical data, OCT scans and high-quality SVP fundal images and videos, to help the development of automated tools to detect and quantify SVPs.
Can't join this trial?
Data last synced from ClinicalTrials.gov: 19 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.