Type 1 Diabetes Trial, Recruiting

Written by an AI model from the ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• You are able to give your own consent to take part in the study
• You are between 18 and 65 years old
• You have been diagnosed with Type 1 diabetes
• You have been using a Tandem t:slim X2 or Tandem Mobi insulin pump with the Control-IQ feature for at least 90 days before the screening visit
• You use insulin aspart or insulin lispro in your Tandem pump
• Your total daily insulin dose is between 20 and 80 units
• Your usual insulin dose for a 50-gram carbohydrate lunch meal is 12 units or less
• You are physically active, doing at least 3 moderate or vigorous exercise sessions of 30 minutes or more per week (self-reported)
• You have no medical, mental health, or other conditions, or medications that the study doctor believes would make participation unsafe
• You have no heart rhythm abnormalities on an ECG (heart tracing) that the study doctor believes would make exercise risky for you
• The study doctor believes you can safely follow the study plan
• You can read and understand written and spoken English or Spanish

Who may not be able to join:

• You have used inhaled insulin in the week before the screening visit
• You have a history of asthma, COPD, cystic fibrosis, or any other significant lung or heart-lung condition
• You have smoked (cigarettes, cigars, pipes, marijuana, or vaping) in the 90 days before the screening visit, or plan to smoke during the study
• You have a history of or current lung cancer
• Your lung function test (measuring how much air you can breathe out in one second) is below 70% of the expected level for your age and body size
• You are pregnant, breastfeeding, planning to become pregnant, or are able to become pregnant and are not using an accepted form of birth control (confirm with trial site)
• You have had a severe low blood sugar episode in the 90 days before the screening visit, as judged by the study doctor
• You have had a diabetic ketoacidosis (DKA) episode in the 90 days before the screening visit
• You have any condition other than diabetes, or take any medication (such as beta blockers), that the study doctor believes may significantly affect your blood sugar levels
• You have used any non-insulin blood sugar-lowering medication, or a weight-loss medication that also lowers blood sugar, in the 4 weeks before the screening visit
• You have taken part in another medical research study involving an experimental drug in the 90 days before the screening visit
• You are currently using or expect to use steroid medications taken by mouth, inhaled, or by injection during the study (skin creams or nasal sprays containing steroids are acceptable)
• You currently use a medication called Hydroxyurea
• You currently follow or plan to follow a very low carbohydrate diet (less than 50 grams per day) or a very low calorie diet (less than 800 calories per day) during the study
• You are currently receiving treatment for diabetic eye disease (diabetic retinopathy)
• You have advanced chronic kidney disease (stage 4 or 5) or are on dialysis
• Your direct work supervisor is involved in running this clinical trial, or a close family member (parent, sibling, or child) is directly involved in running the study

Important: Always verify eligibility with the trial site directly before applying.