Type 1 Diabetes Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- People aged between 18 and 50 years old
- People who have Type 1 Diabetes, use an insulin pump, and wear a continuous glucose monitoring (CGM) device
- People whose average glucose level (measured by a score called GMI) falls between 5.5% and 8.5%, with a normal blood count at the screening visit
- People who have been diagnosed with obstructive sleep apnea (a condition where breathing repeatedly stops during sleep) confirmed by a home sleep test
Who may not be able to join:
- People who are already regularly using a CPAP machine (a device that helps with breathing during sleep) as recommended by their doctor
- People who need oxygen or special breathing support equipment during sleep
- People who have fallen asleep at the wheel or had a near-miss accident due to sleepiness in the past 6 months
- People who work shift work
- People who have had a severe low blood sugar episode in the past 3 months, or who have been diagnosed with a condition where they cannot feel when their blood sugar is low
- People who have visited an emergency room for blood sugar problems in the past 6 months
- People who have advanced diabetes-related eye disease affecting the retina
- People with very high fasting triglyceride (a type of fat in the blood) levels above 400mg/dL
- People with elevated liver enzyme levels more than twice the normal range
- People who have had a kidney transplant or have reduced kidney function (confirm with trial site)
- People with anaemia (low red blood cell levels — below 13.0g/dL for men or below 11.6g/dL for women)
- People who have had a heart attack or stroke in the past 6 months
- People with severely high blood pressure (above 180/105 mmHg)
- People with certain serious heart, lung, thyroid, or other hormonal conditions, including unstable chest pain, heart failure requiring hospitalisation in the past 6 months, significant irregular heart rhythms, serious lung disease requiring oxygen or daily breathing medication, active or ongoing infection, thyroid disease, or conditions such as Cushing's syndrome or acromegaly
- People who have recently had major surgery
- People with a major psychiatric (mental health) disorder
- People currently taking certain medications that may affect metabolism, including steroid tablets, antipsychotic medications, certain blood pressure or fluid tablets, daily asthma medications (aminophylline or theophylline), or immune-suppressing drugs (confirm specific medications with trial site)
- People who are currently pregnant, trying to become pregnant, or breastfeeding
- People who currently smoke, or have issues with alcohol or illegal drug use
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: Esra Tasali, MD, University of Chicago
Phone: 7738342663
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Glycemic variability
Can't join this trial?
Data last synced from ClinicalTrials.gov: 7 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.