Phase 2 Lung Cancer Trial, Recruiting NCT06943820 Sponsor: Akeso Condition: Lung Cancer
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Phase 2 Lung Cancer Trial, Recruiting

NCT06943820
Recruiting Phase 2

voxsanity.com.au · Eligibility summary from public government registries · 18 August 2026 · not medical advice

Who may and may not be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who may be able to join

  • People who are able and willing to sign a consent form and follow all study requirements and procedures
  • People aged 18 to 75 years old (any sex)
  • People who are generally well enough to carry out daily activities with little to no limitation (confirmed by a doctor using a standard health rating scale)
  • People with a life expectancy of more than 3 months
  • People with a confirmed diagnosis of either: advanced non-small cell lung cancer (Stage IIIB/C or IV) who have either received no prior treatment for advanced disease, or who have already received platinum-based chemotherapy combined with an immunotherapy drug and whose cancer has since progressed
  • People with a confirmed diagnosis of recurrent or metastatic head and neck cancer who have either received no prior treatment for that stage of disease, or who have already received platinum-based chemotherapy combined with an immunotherapy drug and whose cancer has since progressed
  • People with a confirmed diagnosis of advanced colorectal cancer of a specific type (adenocarcinoma with stable microsatellites, meaning the cancer does not have a particular genetic instability feature)
  • People whose cancer can be measured on scans according to a standard set of medical criteria
  • People whose organs (such as liver, kidneys, and bone marrow) are functioning well enough to meet the trial's requirements

Who may not be able to join

Each point below is a reason the trial team may not be able to accept someone. It is not a list of requirements to meet.

  • People whose lung cancer has certain specific genetic mutations or gene changes (including EGFR-sensitive mutations, ALK fusion, ROS1 rearrangement, MET exon 14 skipping, EGFR exon 20 insertion, BRAF V600E, NTRK gene fusion, or RET gene fusion), or whose tumour contains small cell carcinoma components
  • People with colorectal cancer that has a specific genetic instability feature (known as MSI-H/dMMR), or whose cancer is confirmed to be a different tissue type than adenocarcinoma
  • People who are currently taking part in another clinical trial
  • People with active cancer that has spread to the brain, brain stem, spinal cord, or the lining around the brain
  • People who have had an active autoimmune disease requiring ongoing medical treatment in the past 2 years
  • People with a known active infection of tuberculosis, syphilis, hepatitis B, or hepatitis C
  • People who have had or currently have non-infectious lung inflammation or scarring that requires treatment with steroid medicines
  • People with fluid build-up around the lungs, heart, or in the abdomen that is causing symptoms or needs to be drained regularly
  • People with a history of heart muscle disease, heart inflammation, or serious irregular heartbeats
  • People with a known allergy to any ingredient in the study drugs, or a history of a severe allergic reaction to other similar antibody-based medicines
  • People who are pregnant or currently breastfeeding

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 31 July 2026

Contact this trial

Phone: +86(0760)89873999

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 2
Sponsor
Akeso
Registry
ClinicalTrials.gov
Start date
21 May 2025
Est. completion
1 December 2026

Where this trial is recruiting

🇨🇳 China

Primary endpoints

Frequency and severity of adverse events (AEs) ,Clinically significant abnormal laboratory results; Overall Response Rate (ORR)

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 31 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov