Gastro-oesophageal Reflux Disease Trial, Recruiting NCT06955520 Sponsor: Asian Institute of Gastroenterology, India Condition: Gastro-oesophageal Reflux Disease
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Gastro-oesophageal Reflux Disease Trial, Recruiting

NCT06955520
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • Adults aged 18 or older
  • People who have previously had a procedure called POEM (Per-Oral Endoscopic Myotomy) to treat a swallowing condition called achalasia
  • People who had a camera examination of their food pipe 3 months after POEM that showed a moderate to severe level of acid-related irritation (graded B, C, or D on a standard scale)
  • People who have been experiencing acid reflux symptoms such as heartburn or bringing up stomach contents for at least 4 weeks
  • People who are willing to give their consent to participate and follow the study requirements

Who may not be able to join:

  • People who have previously had surgery to treat acid reflux
  • People who have a condition called Barrett's esophagus, a narrowing of the food pipe, or any cancer of the food pipe
  • People who have a serious stomach-emptying problem or a food pipe movement disorder that is not related to achalasia
  • People who are pregnant or currently breastfeeding
  • People with serious liver or kidney problems, as measured by specific blood test results falling outside certain ranges (confirm with trial site)
  • People who regularly take certain medications including anti-inflammatory drugs (such as ibuprofen), steroids, or blood-thinning medications that may affect healing of the food pipe

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 23 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Mohan Dr Ramchandani, MD DM, Asian Institute of Gastroenterology

Phone: 04023378888

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Sponsor
Asian Institute of Gastroenterology, India
Registry
ClinicalTrials.gov
Start date
30 April 2025
Est. completion
10 December 2027

Where this trial is recruiting

🇮🇳 India

Primary endpoints

• Endoscopic healing of reflux esophagitis at 8 weeks (absence of LA grade B or higher esophagitis).

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 23 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov