Phase 2 Pancreatic Cancer Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• You are willing to take part and have signed a consent form agreeing to join the study
• You are between 18 and 75 years old (at the time of signing the consent form)
• You have been diagnosed with pancreatic ductal adenocarcinoma (a specific type of pancreatic cancer) confirmed by a tissue or cell sample — not a mixed type of pancreatic cancer
• You have at least one tumor that can be measured on a scan, according to standard criteria
• You have not had any previous systemic (whole-body) cancer treatments
• You are in relatively good general health and able to carry out daily activities (with little or no limitation), and doctors expect you to live for more than 3 months
• Your major organs (such as your heart, liver, and kidneys) are working well
• If you could become pregnant, you must use reliable birth control during the study and for 6 months after it ends, have a negative pregnancy test within 7 days before joining, and must not be breastfeeding

Who may not be able to join:

• You have had or currently have another type of cancer within the past 5 years — with some exceptions: certain fully treated cancers with no return, such as early-stage cervical cancer, skin basal cell carcinoma, certain nasopharyngeal cancers, or superficial bladder tumors may still be eligible (confirm with trial site)
• You still have unresolved side effects (above a mild level) from any previous treatment, not counting hair loss
• You have had major surgery, a serious injury, or have a wound or fracture that has not fully healed within the 28 days before starting the trial treatment
• You have had a significant bleeding event within the 4 weeks before starting the trial treatment
• You have had a serious blood clot event — such as a stroke, mini-stroke, deep vein thrombosis, or pulmonary embolism — within the past 6 months
• You have hepatitis B and cannot receive regular antiviral treatment throughout the study, or you have hepatitis C and your condition is considered unstable or you need ongoing antiviral treatment that cannot be maintained during the study
• You have active syphilis
• You have a history of abusing mind-altering substances that you are unable to stop, or you have a mental health disorder
• You have symptomatic interstitial lung disease or a condition that could increase the risk of lung damage from the study drug
• You have any other severe or uncontrolled medical conditions
• Scans show that your tumor has grown into or very close to major blood vessels, and your doctor believes there is a high risk of serious bleeding
• You have cancer that has spread to the brain or the lining around the brain
• You have fluid build-up around the lungs, heart, or in the abdomen that is not controlled and still requires repeated draining
• You have had a severe allergic reaction to a large-molecule drug in the past, or are known to be allergic to any ingredient in the study drug (TQB2916)
• You have been taking regular steroid medications or other immune-suppressing drugs at a significant dose within the past 28 days and will need to continue them after starting the trial (except for short-term use)
• You have received a live attenuated vaccine (a type of vaccine made with a weakened live virus) within the 28 days before starting the study, or plan to receive one during the study
• You have an active autoimmune disease that needed medical treatment within the 2 years before joining the study
• You have taken part in another clinical trial for a cancer treatment within the 28 days before starting this study
• Your doctor feels that other health conditions or circumstances make it unsafe or unsuitable for you to participate

Important: Always verify eligibility with the trial site directly before applying.