Phase 4 Gout Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• You have been diagnosed with gout according to recognized international medical guidelines (ACR/EULAR 2015 criteria)
• You are between 18 and 70 years old (any gender)
• Your most recent gout attack happened at least 2 weeks ago
• You have been taking a stable dose of uric acid-lowering medication for more than 4 weeks
• If you are a woman who could become pregnant, you must have a negative pregnancy test, not be breastfeeding, and be using an approved form of birth control throughout the study
• You are willing to sign a consent form and agree to attend all required visits, tests, and treatments
• You understand and agree to the purpose and content of the research

Who may not be able to join:

• You are currently having an active gout flare-up
• Your gout is caused by another condition such as kidney disease, a blood disorder, certain medications, or cancer treatment (radiotherapy or chemotherapy)
• You have serious or unstable heart or brain blood vessel conditions (such as unstable chest pain, heart failure, mini-strokes, or similar), uncontrolled serious illnesses, certain rare metabolic conditions, untreated thyroid disease, kidney stones, very high blood pressure (above 160/100 mmHg), severely uncontrolled diabetes, or you have had an organ transplant
• You have a known allergy to any of the study-related medicines, including febuxostat, allopurinol, benzbromarone, etoricoxib, colchicine, or potassium citrate (confirm with trial site)
• You have an active stomach or intestinal ulcer, or an ulcer that has caused bleeding or a perforation, or you have had severe ongoing diarrhea or recurring skin disease in the past year
• Your blood test results show low white blood cell count, low haemoglobin, low platelet count, or you have another blood system disorder such as severe anaemia or a clotting problem
• You have active liver disease or your liver function tests are significantly abnormal
• Your kidneys are not working well enough (based on a specific kidney function measurement) (confirm with trial site)
• Your blood potassium level is too high, or you have a condition that could cause high potassium levels
• Your urine acidity level (pH) is above 6.5 at the screening stage
• You are currently taking certain medications including high-dose aspirin (over 300mg/day), certain water tablets (diuretics), ACE inhibitors, azathioprine, theophylline, losartan, cyclosporin A, cyclophosphamide, long-term insulin, digitalis, or several other specific drugs listed in the study (confirm full list with trial site)
• You are pregnant, planning to become pregnant, or breastfeeding
• You have a mental health condition that affects your ability to understand the study or take medication as required
• You have had a problem with alcohol or drug dependence in the past two years
• You have taken part in another clinical trial in the last three months
• You are a family member or relative of someone working at the research centre
• The study doctor believes there is another reason that makes it unsuitable for you to participate

Important: Always verify eligibility with the trial site directly before applying.