Depression and Anxiety Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- People who are male or female and between 12 and 14 years old
- People who are experiencing symptoms of anxiety
- People who are able to understand and sign an assent form, and whose parents are able to sign a permission and consent document in English
- People who meet the trial's specific hearing and vision requirements (confirm with trial site)
- People who have never used substances such as alcohol, tobacco, or marijuana
Who may not be able to join:
- People who have metal objects or implants in their body, such as bone screws, shunts, or body piercings that cannot be removed
- People who have been diagnosed with psychosis or a severe emotional disturbance
- People who have used alcohol, tobacco, or marijuana more than 3 times
- Girls who are pregnant — the trial site will not include them in the stress evaluation or MRI scan
- People who are currently taking medications that directly affect how the heart and blood vessels work, such as beta blockers like propranolol
- People who are currently taking, or have ever taken, antipsychotic medication
- People who have had a head injury that caused them to lose consciousness for more than 5 minutes
- People who are planning to get non-removable metal braces
- People with significantly impaired intellectual functioning, assessed as a full-scale IQ below 70
- People with a current or past significant condition affecting the brain or nervous system that could interfere with brain imaging results (confirm with trial site)
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: Aysenil Belger, PhD, University of North Carolina, Chapel Hill
Phone: (919)-260-9822
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Reaction time during the functional magnetic resonance imaging (FMRI) Stop Signal Task; Percent signal change during the FMRI Stop Signal Task; Percent signal change activation during the No-stimuli, Predictable-stimuli, and Unpredictable-stimuli (NPU) task; Percent signal change during the Attentional Load Paradigm (ALP) task; Percent signal change during Emotional Face N-Back (EFNBack); Sympathetic and Parasympathetic nervous system ECG activation or heart rate variability (HRV) during a psychosocial stressful task (Trier Social Stress Test - TSST); Endocrine (cortisol) measures during a psy...
Can't join this trial?
Data last synced from ClinicalTrials.gov: 6 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.