Phase 2 Myeloma Trial, Recruiting NCT06988488 Sponsor: Celgene Condition: Myeloma
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Phase 2 Myeloma Trial, Recruiting

NCT06988488
Recruiting Phase 2

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • Adults aged 18 or older who have been diagnosed with multiple myeloma that has come back or stopped responding to treatment, and who have previously received between 2 and 4 rounds of myeloma treatment (for the first phase of the trial) or between 1 and 3 rounds of myeloma treatment (for the second phase of the trial).
  • People whose myeloma can be detected and measured through standard laboratory tests at a local facility.
  • People who are in relatively good general health and able to carry out daily activities with little or no limitation, as assessed by a standard medical scale (called ECOG Performance Status 0 to 1).
  • People who are willing and able to follow the trial's requirements around contraception (confirm with trial site for specific details).

Who may not be able to join:

  • People who have previously been treated with a medication called mezigdomide.
  • People who have previously received a type of treatment that works by engaging or activating T cells (a type of immune cell) to fight the cancer.
  • People who have previously received any treatment that targets a protein called BCMA, unless they received a specific type of personalised cell therapy (autologous BCMA-targeted CAR T-cell therapy) more than 6 months before the start of this trial.
  • There are additional criteria not listed here that the trial site will assess (confirm with trial site for full details).

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 16 July 2026
Phase 2: approximately ~30% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: Bristol-Myers Squibb, Bristol-Myers Squibb

Phone: 855-907-3286

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 2
Sponsor
Celgene
Registry
ClinicalTrials.gov
Start date
7 October 2025
Est. completion
31 May 2027

Where this trial is recruiting

🇨🇦 Canada 🇨🇳 China 🇩🇪 Germany 🇬🇷 Greece 🇳🇴 Norway 🇪🇸 Spain 🇬🇧 United Kingdom 🇺🇸 United States

Primary endpoints

Number of participants with Adverse Events (AEs); Number of participants with Serious AEs; Number of participants with AEs meeting protocol-defined DLT criteria; Number of participants with AEs leading to discontinuation; Number of deaths; Recommended Phase 2 Dose (RP2D)

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 16 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov