Phase 2 Lung Cancer Trial, Not Yet Recruiting NCT07004712 Sponsor: Peking University Cancer Hospital & Institute Condition: Lung Cancer
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Phase 2 Lung Cancer Trial, Not Yet Recruiting

NCT07004712
Not Yet Recruiting Phase 2

voxsanity.com.au · Eligibility summary from public government registries · 18 August 2026 · not medical advice

Who may and may not be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who may be able to join

  • Adults between 18 and 75 years of age.
  • People who have been diagnosed with small cell lung cancer confirmed by a tissue sample (biopsy); combined/mixed types of small cell lung cancer are not allowed.
  • People whose cancer has continued to grow or spread after receiving first-line chemotherapy combined with immunotherapy (including PD-1 or PD-L1 inhibitor treatments).
  • People who have at least one tumour that can be measured using standard imaging criteria (RECIST 1.1).
  • People with a performance status score of 0 or 1 on the ECOG scale, meaning they are fully active or have only mild limitations in physical activity (confirm with trial site).
  • People whose blood, liver, and kidney function test results meet specific minimum levels set by the trial, including adequate white blood cell counts, platelet counts, haemoglobin, liver enzyme levels, and kidney function measures (confirm with trial site for exact values).
  • People with an expected survival of more than 12 weeks.
  • People who are willing and able to follow the planned treatment schedule, understand the study process, and sign a written consent form.

Who may not be able to join

Each point below is a reason the trial team may not be able to accept someone. It is not a list of requirements to meet.

  • People who have previously been treated with irinotecan liposome or irinotecan.
  • People with serious heart or lung disease, including those with heart disease rated at Grade II or above on the New York Heart Association (NYHA) scale.
  • People with a severe active infection or other serious illness affecting the whole body.
  • People known to have an allergy or intolerance to chemotherapy drugs or their ingredients.
  • People who have had another cancer diagnosis in the past 5 years, except for certain cured cancers such as cervical carcinoma in situ or non-melanoma skin cancer.
  • People who are pregnant or breastfeeding, or people of childbearing age who are not willing to use appropriate contraception during the study.
  • People who have taken part in another clinical drug study within 21 days before the first dose of the study drug.
  • People with active autoimmune diseases or active inflammatory conditions.
  • People who experienced severe (Grade 3 or 4) immune-related side effects during previous immunotherapy treatment.
  • People with brain metastases or cancer spread to the membranes around the brain that are causing symptoms.
  • People who are currently taking long-term oral corticosteroids (such as prednisone at more than 10mg per day or an equivalent dose) or any form of immunosuppressive therapy before the first dose; note that people who need inhalers, topical steroids, or local steroid injections may still be considered.
  • People with a large build-up of fluid in body cavities, or fluid that is causing symptoms, or fluid that has been difficult to control (defined as needing drainage two or more times within one month).
  • People whom the study doctor judges to be unsuitable for participation for any other reason.

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 7 July 2026

Contact this trial

Phone: +86-010-88197863

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Not Yet Recruiting
Phase
Phase 2
Sponsor
Peking University Cancer Hospital & Institute
Registry
ClinicalTrials.gov
Start date
1 June 2025
Est. completion
1 March 2028

Where this trial is recruiting

🇨🇳 China

Primary endpoints

Progression Free Survival (PFS)

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 7 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov