Type 1 Diabetes Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• People who are 18 years old or older at the time of signing consent
• People who have been clinically diagnosed with Type 1 Diabetes for at least one year, based on a doctor's assessment
• People who have used an FDA-approved automated insulin delivery (AID) system at some point in the last six months, even if not used every day
• People who have been using insulin for at least six months
• People who are willing to switch to a specific FDA-approved insulin for the study pump (such as lispro or aspart, or an approved biosimilar), as directed by the study team
• People who have at least one support person — such as a friend or family member — who knows how to respond to a severe low blood sugar emergency, can contact emergency services and study staff, and either lives with the participant or is within about 30 minutes away and able to locate them in an emergency
• People who are not currently known to be pregnant or breastfeeding
• People who could become pregnant and agree to use a reliable form of contraception (such as hormonal contraception or not having heterosexual intercourse) for the duration of the study, and who receive a negative pregnancy test before starting
• People who are willing to wear a Dexcom continuous glucose monitor (CGM) throughout all four phases of the study
• People who are willing to use the study's full technology system (CGM, insulin pump, and phone) during the relevant study periods
• People who are willing not to start any new non-insulin blood sugar-lowering medications during the trial
• People who are willing to take part in all study procedures, including attending in-person training sessions
• People who have internet access at home and are willing to upload study data when required
• People whom the study investigator is confident can correctly use all study devices and follow the study plan
• People who can read and speak English fluently

Who may not be able to join:

• People planning to start a new non-insulin blood sugar-lowering medication (such as GLP-1 receptor agonists, Symlin, or DPP-4 inhibitors) — note that people already on a stable dose of such a medication for at least one month may still be considered (confirm with trial site)
• People currently taking a type of diabetes medication called a sulfonylurea
• People currently taking a type of medication known as an SGLT-2 or SGLT-1/2 inhibitor (such as certain newer diabetes pills), due to the risk of a serious condition called diabetic ketoacidosis
• People with haemophilia or any other bleeding disorder
• People who have had a severe low blood sugar episode involving a seizure or loss of consciousness in the past 12 months
• People who have had a diabetic ketoacidosis (DKA) episode in the past 12 months
• People currently receiving peritoneal dialysis or haemodialysis (kidney dialysis treatments)
• People currently being treated for adrenal insufficiency (a condition where the adrenal glands do not produce enough hormones)
• People currently being treated for a seizure disorder
• People with a thyroid condition (underactive or overactive thyroid) that is not well managed with treatment
• People currently using oral or injectable steroid medications at the time of enrolment
• People with a known ongoing skin adhesive intolerance that is not well managed
• People with any other condition that the study investigator believes would put the participant or the study at risk
• People already participating in another interventional clinical trial at the time of enrolment
• People whose direct manager or supervisor at work or school is involved in running this trial

Important: Always verify eligibility with the trial site directly before applying.